Pomalidomide-7-NH2

Modify Date: 2024-01-09 18:20:57

Pomalidomide-7-NH2 structure	Common Name	Pomalidomide-7-NH2
	CAS Number	497146-96-0	Molecular Weight	288.26
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₂N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pomalidomide-7-NH2

Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].

Name	Pomalidomide-7-NH2

Description	Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-994.

Molecular Formula	C₁₃H₁₂N₄O₄
Molecular Weight	288.26
Storage condition	2-8°C

DC Chemicals Limited
China
Product Name: Pomalidomide-7-NH2
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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Pomalidomide-7-NH2

Use of Pomalidomide-7-NH2

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Pomalidomide-7-NH2 Biological Activity

Chemical & Physical Properties