Pomalidomide-7-NH2
Modify Date: 2024-01-09 18:20:57
Pomalidomide-7-NH2 structure
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Common Name | Pomalidomide-7-NH2 | ||
|---|---|---|---|---|
| CAS Number | 497146-96-0 | Molecular Weight | 288.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H12N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Pomalidomide-7-NH2Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1]. |
| Name | Pomalidomide-7-NH2 |
|---|
| Description | Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C13H12N4O4 |
|---|---|
| Molecular Weight | 288.26 |
| Storage condition | 2-8°C |