Sclareol
Sclareol structure
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Common Name | Sclareol | ||
|---|---|---|---|---|
| CAS Number | 515-03-7 | Molecular Weight | 308.499 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 398.3±15.0 °C at 760 mmHg | |
| Molecular Formula | C20H36O2 | Melting Point | 95-100 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 169.1±15.0 °C | |
Use of SclareolSclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. |
Summary: Sclareol, Chinese name: 香紫苏醇, CAS number: 515-03-7, molecular formula: C20H36O2, molecular weight: 308.499. White fine powder, melting point: 95-100 °C, boiling point: 398.3±15.0 °C, density: 1.0±0.1 g/cm3. Mainly used in perfumes, fragrances, cigarettes, cosmetics, health food, food additives, etc. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | sclareol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. |
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| Related Catalog | |
| In Vitro | Sclareol is cytotoxic to 13 of 14 human leukemia cell lines tested, with IC50 values ranging from 6.0–24.2 μg/mL, but is not cytotoxic to peripheral blood mononuclear leukocytes within the same dose range[1]. |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 398.3±15.0 °C at 760 mmHg |
| Melting Point | 95-100 °C(lit.) |
| Molecular Formula | C20H36O2 |
| Molecular Weight | 308.499 |
| Flash Point | 169.1±15.0 °C |
| Exact Mass | 308.271515 |
| PSA | 40.46000 |
| LogP | 5.54 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.490 |
| InChIKey | XVULBTBTFGYVRC-HHUCQEJWSA-N |
| SMILES | C=CC(C)(O)CCC1C(C)(O)CCC2C(C)(C)CCCC21C |
| Storage condition | 2-8C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | QK0301900 |
| HS Code | 2906199090 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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Sclareol CAS#:515-03-7
Learn More
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| Literature: Rogachev, Victor; Loehl, Thorsten; Markert, Thomas; Metz, Peter Arkivoc, 2012 , vol. 2012, # 3 p. 172 - 180 |
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Sclareol CAS#:515-03-7
Learn More
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| Literature: Leite, Mary Ann F.; Sarragiotto, Maria Helena; Imamura, Paulo M.; Marsaioli, Anita J. Journal of Organic Chemistry, 1986 , vol. 51, # 26 p. 5409 - 5410 |
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Sclareol CAS#:515-03-7
Learn More
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| Literature: Scheidegger,U. et al. Helvetica Chimica Acta, 1962 , vol. 45, p. 400 - 435 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 3 | |
|---|---|
| DownStream 9 | |
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CAS#:1227-93-6This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2906199090 |
|---|---|
| Summary | 2906199090. cyclanic, cyclenic or cyclotherpenic alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Parallel dual secondary column-dual detection: a further way of enhancing the informative potential of two-dimensional comprehensive gas chromatography.
J. Chromatogr. A. 1360 , 264-74, (2014) Comprehensive two-dimensional gas chromatography (GC×GC) coupled with Mass Spectrometry (MS) is one of today's most powerful analytical platforms for detailed analysis of medium-to-high complexity sam... |
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Labdane diterpenoids from Salvia reuterana.
Phytochemistry 108 , 264-9, (2014) Three labdane diterpenoids, 14α-hydroxy-15-chlorosclareol (1), 14α-hydroxy-15-acetoxysclareol (2), and 6β-hydroxy-14α-epoxysclareol (3), together with the known diterpenoids sclareol (4), 6β-hydroxysc... |
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Isolation, chemical, and biotransformation routes of labdane-type diterpenes.
Chem. Rev. 111(8) , 4418-52, (2011)
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This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-methyl-4-penten-1-yl]-2,5,5,8a-tetramethyldecahydro-2-naphthalenol |
| (1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol |
| SCLAREOL(RG) |
| EINECS 208-194-0 |
| SCIADONIC ACID |
| (1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol |
| labd-14-ene-8,13(R)-diol |
| MFCD00869558 |
| SCLAREOL,NATURAL |
| SCAREOL |
| Sclareol |
| (-)-sclareol |
| SCLAREOL(P) |
| (1R,2R,4aS,8aS)-1-[(3R)-3-Hydroxy-3-méthyl-4-pentèn-1-yl]-2,5,5,8a-tétraméthyldécahydro-2-naphtalénol |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the melting point of sclareol? |
| A: Melting point of sclareol is 95-100 °C(lit.). |
| Q: What is the molecular formula of sclareol? |
| A: Molecular formula of sclareol is C20H36O2. |
| Q: What is the English name of sclareol? |
| A: The English name of sclareol is sclareol. |
| Q: What are the upstream materials of sclareol? |
| A: Related upstream materials(CAS) of sclareol: 54274-72-5;1158-77-6;596-85-0. |
| Q: What is the boiling point of sclareol? |
| A: Boiling point of sclareol is 398.3±15.0 °C at 760 mmHg. |
| Q: What are the uses of sclareol? |
| A: Main uses of sclareol: Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. |
| Q: What is the LogP of sclareol? |
| A: LogP of sclareol is 5.54. |
| Q: What is the SMILES notation of sclareol? |
| A: SMILES notation of sclareol is C=CC(C)(O)CCC1C(C)(O)CCC2C(C)(C)CCCC21C. |
| Q: What are the storage conditions for sclareol? |
| A: Storage conditions for sclareol: 2-8C. |
| Q: What is the CAS number of sclareol? |
| A: CAS number of sclareol is 515-03-7. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| BioBioPha |
| naturewill |
| Henan Tianfu Chemical Co., Ltd. |
| Zhongshan Xingrui Chemical Co. , Ltd. |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Sclareol
- Price: Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- BioBioPha
- China
- Product Name: Sclareol
- Price: ￥Inquiry/5mg
- Purity: 95.0%
- Delivery: 10 Day
- Contact: Xueping-Zheng
- Email: 1477035482@qq.com
- naturewill
- China
- Product Name: Sclareol
- Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Bella
- Email: 3157321941@qq.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Sclareol 515-03-7
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
- Zhongshan Xingrui Chemical Co. , Ltd.
- China
- Product Name: Sclareol
- Price: ￥1550.0/1kg
- Purity: 95.0%
- Delivery: 3 Day
- Contact: Wang Jie
- Email: 3096638339@qq.com
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