ESI 05

Modify Date: 2024-01-11 20:18:50

ESI 05 structure	Common Name	ESI 05
	CAS Number	5184-64-5	Molecular Weight	274.37800
	Density	1.129g/cm3	Boiling Point	426.7ºC at 760mmHg
	Molecular Formula	C₁₆H₁₈O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	250ºC

Use of ESI 05

ESI-05 (NSC 116966) is a specific exchange protein directly activated by cAMP 2 (EPAC2) antagonist (IC50, 0.4 µM), suppresses the cAMP-mediated activation of EPAC2 and inhibits Rap1 activation mediated by EAPC2[1].

Name	1,3,5-trimethyl-2-(4-methylphenyl)sulfonylbenzene
Synonym	More Synonyms

Description	ESI-05 (NSC 116966) is a specific exchange protein directly activated by cAMP 2 (EPAC2) antagonist (IC50, 0.4 µM), suppresses the cAMP-mediated activation of EPAC2 and inhibits Rap1 activation mediated by EAPC2[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 0.4 µM (EPAC2)[1]
References	[1]. Tsalkova T, et al. Isoform-specific antagonists of exchange proteins directly activated by cAMP. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18613-8.

Density	1.129g/cm3
Boiling Point	426.7ºC at 760mmHg
Molecular Formula	C₁₆H₁₈O₂S
Molecular Weight	274.37800
Flash Point	250ºC
Exact Mass	274.10300
PSA	42.52000
LogP	4.83380
Index of Refraction	1.562

Precursor 10
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DownStream 0

mesityl(4-methylphenyl) sulfone

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ESI-05
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ESI-05
Price: $250.0/100mg $450.0/250mg $900.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: ESI-05
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Benzene,1,3,5-trimethyl-2-[(4-methylphenyl)sulfonyl]-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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