m-PEG5-SH

Modify Date: 2024-01-08 21:19:09

m-PEG5-SH Structure
m-PEG5-SH structure
Common Name m-PEG5-SH
CAS Number 524030-00-0 Molecular Weight 268.37000
Density 1.048 Boiling Point N/A
Molecular Formula C11H24O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG5-SH


m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanethiol
Synonym More Synonyms

 m-PEG5-SH Biological Activity

Description m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.048
Molecular Formula C11H24O5S
Molecular Weight 268.37000
Exact Mass 268.13400
PSA 84.95000
LogP 0.62900
Storage condition 2-8°C

 Synonyms

3,6,9,12,15-pentaoxahexadecane-1-thiol
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