ARC 239 dihydrochloride
Modify Date: 2024-01-16 21:02:13
ARC 239 dihydrochloride structure
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Common Name | ARC 239 dihydrochloride | ||
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| CAS Number | 55974-42-0 | Molecular Weight | 480.42700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H31Cl2N3O3 | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | N/A | |
Use of ARC 239 dihydrochlorideARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pKd values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pKis of 5.6, 8.4, and 7.08, respectively[1]. |
| Name | 2-{2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl}-4,4-dimethyl-1,3(2 H,4H)-isoquinolinedione dihydrochloride |
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| Synonym | More Synonyms |
| Description | ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist (pKd values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pKis of 5.6, 8.4, and 7.08, respectively[1]. |
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| Related Catalog | |
| Target |
Alpha-2B adrenergic receptor 5-HT1A Receptor |
| References |
| Molecular Formula | C24H31Cl2N3O3 |
|---|---|
| Molecular Weight | 480.42700 |
| Exact Mass | 479.17400 |
| PSA | 53.09000 |
| LogP | 4.32220 |
| Pertussis Toxin |