LD 490

Modify Date: 2024-01-02 11:39:19

LD 490 Structure
LD 490 structure
Common Name LD 490
CAS Number 58336-35-9 Molecular Weight 241.28500
Density 1.32g/cm3 Boiling Point 486.3ºC at 760 mmHg
Molecular Formula C15H15NO2 Melting Point 130 °C
MSDS N/A Flash Point 201ºC

 Use of LD 490


Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions[1][2].

 Names

Name Coumarin 6H
Synonym More Synonyms

 LD 490 Biological Activity

Description Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions[1][2].
Related Catalog
In Vitro 具有扭曲嵌段和更强供电子久洛利定基团的 Coumarin 6H 在被荧光猝灭基团抑制时表现出更高的量子产率、更好的生物相容性以及更少的背景荧光。因此,探针 LH-1 中的 Coumarin 6H 可能有助于降低背景荧光。在探针LH-1中,Coumarin 6H 荧光团的荧光不仅可以被 N-N 基团的旋转猝灭,还可以通过供体激发光诱导电子转移 (d-PET) 机制被 2,4-二硝基苯基团猝灭[2]。
References

[1]. P M French, et al. Passively mode-locked cw Coumarin 6 ring dye laser. Opt Lett. 1989 Feb 15;14(4):217-8.  

[2]. Zhixiang Han, et al. A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish. Anal Biochem. 2020 Aug 1;602:113795.  

 Chemical & Physical Properties

Density 1.32g/cm3
Boiling Point 486.3ºC at 760 mmHg
Melting Point 130 °C
Molecular Formula C15H15NO2
Molecular Weight 241.28500
Flash Point 201ºC
Exact Mass 241.11000
PSA 33.45000
LogP 2.55680
Index of Refraction 1.665

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ3310000
CHEMICAL NAME :
1H,5H,11H-(1)Benzopyrano(6,7,8-ij)quinolizin-11-one, 2,3,6,7-tetrahydro-
CAS REGISTRY NUMBER :
58336-35-9
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C15-H15-N-O2
MOLECULAR WEIGHT :
241.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,511,1985

 Synonyms

C 6H
2,3,6,7-tetrahydro-1H,5H-quinolizino<9,9a,1-gh>coumarin
2,3,6,7-tetrahydro-1H,5H,11H-benzopyrano<6,7,8-i,j>quinolizin-11-one
Exciton LD 490
2,3,5,6-1H,4H-tetrahydroquinolizino[9,9a,1-gh]coumarin
MFCD00227485
coumarin-6H
2,3,6,7-Tetrahydro-1H,5H,11H-(1)benzopyrano(6,7,8-ij)-quinolizin-11-one
EINECS 261-213-4
LD 490
2,3,6,7-tetrahydro-1H,5H,11H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11-one
2,3,5,6-Tetrahydro-1H,4H-11-oxa-3a-aza-benzo[de]anthracen-10-one
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