4,4'-Methylenediphenol

Modify Date: 2026-07-03 18:04:26

4,4'-Methylenediphenol structure	Common Name	4,4'-Methylenediphenol
	CAS Number	620-92-8	Molecular Weight	200.233
	Density	1.2±0.1 g/cm3	Boiling Point	390.0±22.0 °C at 760 mmHg
	Molecular Formula	C₁₃H₁₂O₂	Melting Point	162-164 °C
	MSDS	Chinese USA	Flash Point	192.9±16.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of 4,4'-Methylenediphenol

4,4'-Dihydroxydiphenylmethane is a phenolic derivative with antioxidant activities[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	4,4-Dihydroxydiphenylmethane
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	4,4'-Dihydroxydiphenylmethane is a phenolic derivative with antioxidant activities[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. L Yi-Ming, et al. New Phenolic Derivatives from Galeola faberi. Planta Med. 1993 Aug;59(4):363-5.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	1.2±0.1 g/cm3
Boiling Point	390.0±22.0 °C at 760 mmHg
Melting Point	162-164 °C
Molecular Formula	C₁₃H₁₂O₂
Molecular Weight	200.233
Flash Point	192.9±16.9 °C
Exact Mass	200.083725
PSA	40.46000
LogP	2.73
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.635
InChIKey	PXKLMJQFEQBVLD-UHFFFAOYSA-N
SMILES	Oc1ccc(Cc2ccc(O)cc2)cc1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

4,4'-Methylenediphenol MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL9625000

CHEMICAL NAME :: Phenol, 4,4'-methylenebis-

CAS REGISTRY NUMBER :: 620-92-8

BEILSTEIN REFERENCE NO. :: 2049425

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C13-H12-O2

MOLECULAR WEIGHT :: 200.25

WISWESSER LINE NOTATION :: QR D1R DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4950 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	SL9625000
HS Code	2907299090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:611-99-4 4,4'-Dihydroxyb... CAS#:486-25-9 9-Fluorenone CAS#:108-95-2 Phenol CAS#:3277-26-7 1,1,3,3-Tetrame...
CAS#:1745-81-9 2-Allylphenol CAS#:69552-26-7 bis(4-hydroxyph... CAS#:122-25-8 5,5'-Methylened... CAS#:50-00-0 Formaldehyde
CAS#:726-18-1 Benzene,1,1'-me... CAS#:623-05-2 4-Hydroxybenzyl...
DownStream 10
CAS#:500-85-6 indophenol CAS#:21825-03-6 4,4'-methyleneb... CAS#:2150-58-5 phenol blue CAS#:90-96-0 DMBP
CAS#:91-22-5 leucoline CAS#:99-96-7 4-Hydroxybenzoi... CAS#:108-95-2 Phenol CAS#:123-08-0 4-hydroxybenzal...
CAS#:123-31-9 Hydroquinone CAS#:3046-82-0 5-[(3-formyl-4-...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2907299090
Summary	2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Determination of bisphenols in beverages by mixed-mode solid-phase extraction and liquid chromatography coupled to tandem mass spectrometry.

J. Chromatogr. A. 1422 , 230-8, (2015)

Facing growing restrictions on the use of bisphenol A in food contact materials, several bisphenol analogs are arising as major alternatives to replace this chemical in most of its applications. This ...

A simple method for the enrichment of bisphenols using boron nitride.

Food Chem. 194 , 149-55, (2015)

A simple solid-phase extraction method for the enrichment of 5 bisphenol derivatives using hexagonal boron nitride (BN) was developed. BN was applied to concentrate bisphenol derivatives in spiked wat...

Screening of bisphenol A, triclosan and paraben analogues as modulators of the glucocorticoid and androgen receptor activities.

Toxicol. In Vitro 29(1) , 8-15, (2014)

A homeostasis of the glucocorticoid and androgen endocrine system is essential to human health. Their disturbance can lead to various diseases, for example cardiovascular, inflammatory and autoimmune ...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Antifungal activity against Penicillium chrysogenum IBWF assessed as reduction in fun...
Source: ChEMBL
Target: Penicillium chrysogenum
External Id: CHEMBL5124711

Name: Antifungal activity against Paecilomyces variotii ETH 114646 assessed as reduction in...
Source: ChEMBL
Target: Paecilomyces variotii
External Id: CHEMBL5124712

Total 215, Current Page 1 of 22

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

bisphenol F

4,4'-Methylenediphenol

4,4'-Methandiyldibenzolol

4,4'-methylenebis-phenol

EINECS 210-658-2

MFCD00002385

4,4'-DIHYDROXYDIPHENYLMETHANE

4,4'-methanediyldiphenol

4,4'-methylenebis(phenol)

4-[(4-hydroxyphenyl)methyl]phenol

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 4,4-Dihydroxydiphenylmethane?

A: Polar surface area (PSA) of 4,4-Dihydroxydiphenylmethane is 40.46000.

Q: What is the English name of 4,4-Dihydroxydiphenylmethane?

A: The English name of 4,4-Dihydroxydiphenylmethane is 4,4-Dihydroxydiphenylmethane.

Q: What is the CAS number of 4,4-Dihydroxydiphenylmethane?

A: CAS number of 4,4-Dihydroxydiphenylmethane is 620-92-8.

Q: What is the LogP of 4,4-Dihydroxydiphenylmethane?

A: LogP of 4,4-Dihydroxydiphenylmethane is 2.73.

Q: What is the melting point of 4,4-Dihydroxydiphenylmethane?

A: Melting point of 4,4-Dihydroxydiphenylmethane is 162-164 °C.

Q: What English synonyms does 4,4-Dihydroxydiphenylmethane have?

A: English synonyms of 4,4-Dihydroxydiphenylmethane: bisphenol F, 4,4'-Methylenediphenol, 4,4'-Methandiyldibenzolol, 4,4'-methylenebis-phenol, EINECS 210-658-2, MFCD00002385, 4,4'-DIHYDROXYDIPHENYLMETHANE, 4,4'-methanediyldiphenol, 4,4'-methylenebis(phenol), 4-[(4-hydroxyphenyl)methyl]phenol.

Q: What is the InChIKey of 4,4-Dihydroxydiphenylmethane?

A: InChIKey of 4,4-Dihydroxydiphenylmethane is PXKLMJQFEQBVLD-UHFFFAOYSA-N.

Q: What are the uses of 4,4-Dihydroxydiphenylmethane?

A: Main uses of 4,4-Dihydroxydiphenylmethane: 4,4'-Dihydroxydiphenylmethane is a phenolic derivative with antioxidant activities[1].

Q: What is the boiling point of 4,4-Dihydroxydiphenylmethane?

A: Boiling point of 4,4-Dihydroxydiphenylmethane is 390.0±22.0 °C at 760 mmHg.

Q: What is the SMILES notation of 4,4-Dihydroxydiphenylmethane?

A: SMILES notation of 4,4-Dihydroxydiphenylmethane is Oc1ccc(Cc2ccc(O)cc2)cc1.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

BioBioPha

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4,4'-Methylenediphenol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

BioBioPha
China
Product Name: 4,4'-Methylenediphenol
Price: ￥Inquiry/5mg
Purity: 98.0%
Delivery: 10 Day
Contact: Xueping-Zheng
Email: 1477035482@qq.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4,4'-Methylenediphenol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 4,4'-DIHYDROXYDIPHENYLMETHANE
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 4,4'-Methylenediphenol
Price: ￥Inquiry/1kg ￥Inquiry/25kg ￥Inquiry/200kg
Purity: 99.0%
Delivery: 3 Day
Contact: Wang Jie
Email: 3096638339@qq.com

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4,4'-Methylenediphenol

Use of 4,4'-Methylenediphenol

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