Desoxycorticosterone

Modify Date: 2024-01-02 17:09:57

Desoxycorticosterone Structure
Desoxycorticosterone structure
Common Name Desoxycorticosterone
CAS Number 64-85-7 Molecular Weight 330.46100
Density 1.15 g/cm3 Boiling Point 488ºC at 760 mmHg
Molecular Formula C21H30O3 Melting Point 138-144 °C
MSDS Chinese USA Flash Point 263.1ºC
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

 Use of Desoxycorticosterone


Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.

 Names

Name 11-deoxycorticosterone
Synonym More Synonyms

 Desoxycorticosterone Biological Activity

Description Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. KAGAWA CM, et al. Action of new steroids in blocking effects of aldosterone and desoxycorticosterone on salt. Science. 1957 Nov 15;126(3281):1015-6.

 Chemical & Physical Properties

Density 1.15 g/cm3
Boiling Point 488ºC at 760 mmHg
Melting Point 138-144 °C
Molecular Formula C21H30O3
Molecular Weight 330.46100
Flash Point 263.1ºC
Exact Mass 330.21900
PSA 54.37000
LogP 3.69590
Index of Refraction 1.559
Storage condition 2-8℃
Water Solubility slightly soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HG0350000
CHEMICAL NAME :
11-Deoxycorticosterone
CAS REGISTRY NUMBER :
64-85-7
LAST UPDATED :
199703
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C21-H30-O3
MOLECULAR WEIGHT :
330.51
WISWESSER LINE NOTATION :
L E5 B666 OV MUTJ A E FV1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
DOSE :
14500 ug/kg
SEX/DURATION :
female 7 day(s) pre-mating female 1-22 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - delayed effects
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Parenteral
DOSE :
8750 ug/kg
SEX/DURATION :
female 7 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Human Liver
DOSE/DURATION :
2 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 370,49,1996

 Safety Information

Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger
Hazard Statements H225-H301 + H311 + H331-H370
Precautionary Statements P210-P260-P280-P301 + P310-P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R40;R48
Safety Phrases S22-S24/25
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS HG0350000
HS Code 2942000000

 Synthetic Route

 Customs

HS Code 2942000000

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 Synonyms

EINECS 200-596-4
Desoxycorticosterone
(8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
MFCD00003661
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