3M-011
Modify Date: 2023-01-16 19:50:27
3M-011 structure
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Common Name | 3M-011 | ||
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| CAS Number | 642473-62-9 | Molecular Weight | 391.488 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 624.7±65.0 °C at 760 mmHg | |
| Molecular Formula | C18H25N5O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 331.6±34.3 °C | |
Use of 3M-011A potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice. |
| Name | N-{1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methyl-2-propanyl}methanesulfonamide |
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| Synonym | More Synonyms |
| Description | A potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice. |
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| References | References 1. Martinson JA, et al. Cell Immunol. 2007 Nov-Dec;250(1-2):75-84. 2. Hammerbeck DM, et al. Antiviral Res. 2007 Jan;73(1):1-11. View Related Products by Target Toll-like Receptor (TLR) |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 624.7±65.0 °C at 760 mmHg |
| Molecular Formula | C18H25N5O3S |
| Molecular Weight | 391.488 |
| Flash Point | 331.6±34.3 °C |
| Exact Mass | 391.167816 |
| LogP | 1.91 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.643 |
| Methanesulfonamide, N-[2-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl]- |
| N-{1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methyl-2-propanyl}methanesulfonamide |