trans-4-Carboxy-L-proline

Modify Date: 2024-01-04 17:39:27

trans-4-Carboxy-L-proline Structure
trans-4-Carboxy-L-proline structure
Common Name trans-4-Carboxy-L-proline
CAS Number 64769-66-0 Molecular Weight 159.14000
Density 1.456 g/cm3 Boiling Point 355.3ºC at 760 mmHg
Molecular Formula C6H9NO4 Melting Point N/A
MSDS Chinese USA Flash Point 168.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of trans-4-Carboxy-L-proline


Trans-4-Carboxy-L-prolineis a selective glutamate transporter inhibitor[1].

 Names

Name (2S,4R)-pyrrolidine-2,4-dicarboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.456 g/cm3
Boiling Point 355.3ºC at 760 mmHg
Molecular Formula C6H9NO4
Molecular Weight 159.14000
Flash Point 168.7ºC
Exact Mass 159.05300
PSA 86.63000
Index of Refraction 1.534

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles28

More Articles
Evidence for a role of GABA- and glutamate-gated chloride channels in olfactory memory.

Pharmacol. Biochem. Behav. 103(1) , 69-75, (2012)

In the honeybee, we investigated the role of transmissions mediated by GABA-gated chloride channels and glutamate-gated chloride channels (GluCls) of the mushroom bodies (MBs) on olfactory learning us...

Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors.

Bioorg. Med. Chem. Lett. 16(12) , 3268-72, (2006)

A series of substituted pyrrolidine-2,4-dicarboxylic acid amides were synthesized as potential antidiabetic agents, and many of them showed good in vitro DPP-IV inhibition (IC50 = 2-250 nM) with selec...

The effects of local perfusion of DAMGO on extracellular GABA and glutamate concentrations in the rostral ventromedial medulla.

J. Neurochem. 104(3) , 806-17, (2008)

Electrophysiological data suggest an involvement of rostral ventromedial medulla (RVM) GABA and glutamate (GLU) neurons in morphine analgesia. Direct evidence that extracellular concentrations of GABA...

 Synonyms

L-trans-pyrrolidine-2,4-dicarboxylic acid
MFCD00153866
Quipazine dimaleate
trans-4-Carboxy-L-proline
t-2,4-PDC
L-trans-PDC
t-PDC