trans-4-Carboxy-L-proline

Modify Date: 2025-08-27 01:28:34

trans-4-Carboxy-L-proline Structure
trans-4-Carboxy-L-proline structure
Common Name trans-4-Carboxy-L-proline
CAS Number 64769-66-0 Molecular Weight 159.14000
Density 1.456 g/cm3 Boiling Point 355.3ºC at 760 mmHg
Molecular Formula C6H9NO4 Melting Point N/A
MSDS Chinese USA Flash Point 168.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of trans-4-Carboxy-L-proline


Trans-4-Carboxy-L-prolineis a selective glutamate transporter inhibitor[1].

 Names

Name (2S,4R)-pyrrolidine-2,4-dicarboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.456 g/cm3
Boiling Point 355.3ºC at 760 mmHg
Molecular Formula C6H9NO4
Molecular Weight 159.14000
Flash Point 168.7ºC
Exact Mass 159.05300
PSA 86.63000
Index of Refraction 1.534
InChIKey NRSBQSJHFYZIPH-DMTCNVIQSA-N
SMILES O=C(O)C1CNC(C(=O)O)C1

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles28

More Articles
Evidence for a role of GABA- and glutamate-gated chloride channels in olfactory memory.

Pharmacol. Biochem. Behav. 103(1) , 69-75, (2012)

In the honeybee, we investigated the role of transmissions mediated by GABA-gated chloride channels and glutamate-gated chloride channels (GluCls) of the mushroom bodies (MBs) on olfactory learning us...

Substituted pyrrolidine-2,4-dicarboxylic acid amides as potent dipeptidyl peptidase IV inhibitors.

Bioorg. Med. Chem. Lett. 16(12) , 3268-72, (2006)

A series of substituted pyrrolidine-2,4-dicarboxylic acid amides were synthesized as potential antidiabetic agents, and many of them showed good in vitro DPP-IV inhibition (IC50 = 2-250 nM) with selec...

The effects of local perfusion of DAMGO on extracellular GABA and glutamate concentrations in the rostral ventromedial medulla.

J. Neurochem. 104(3) , 806-17, (2008)

Electrophysiological data suggest an involvement of rostral ventromedial medulla (RVM) GABA and glutamate (GLU) neurons in morphine analgesia. Direct evidence that extracellular concentrations of GABA...

 Synonyms

L-trans-pyrrolidine-2,4-dicarboxylic acid
MFCD00153866
Quipazine dimaleate
trans-4-Carboxy-L-proline
t-2,4-PDC
L-trans-PDC
t-PDC
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