Dihydrothymine

Modify Date: 2026-07-02 10:51:46

Dihydrothymine Structure
Dihydrothymine structure
Common Name Dihydrothymine
CAS Number 696-04-8 Molecular Weight 128.12900
Density 1.149 g/cm3 Boiling Point N/A
Molecular Formula C5H8N2O2 Melting Point 263-265°C
MSDS N/A Flash Point N/A

 Use of Dihydrothymine


5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].

 Names

Name 5,6-dihydrothymine
Synonym More Synonyms

 Dihydrothymine Biological Activity

Description 5,6-Dihydro-5-methyluracil (Dihydrothymine), an intermediate breakdown product of thymine, comes from animal or plants. 5,6-Dihydro-5-methyluracil (Dihydrothymine) can be toxic when present at abnormally high levels[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Yamane T, et al. Dihydrothymine from UV-irradiated DNA. Proc Natl Acad Sci U S A. 1967 Aug;58(2):439-42.

 Chemical & Physical Properties

Density 1.149 g/cm3
Melting Point 263-265°C
Molecular Formula C5H8N2O2
Molecular Weight 128.12900
Exact Mass 128.05900
PSA 58.20000
LogP 0.11950
Index of Refraction 1.452
InChIKey NBAKTGXDIBVZOO-UHFFFAOYSA-N
SMILES CC1CNC(=O)NC1=O
Storage condition ?20°C

 Safety Information

Safety Phrases S22-S24/25
HS Code 2933599090

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 DihydrothymineBioassay

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Name: Drug screen in LFS_MB_P medulloblastoma cells to determine synergistic drug combinati...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_LFS_MB_P
Name: Drug screen in ICB984 medulloblastoma cells to determine synergistic drug combination...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_ICB984_MB
Name: Drug screen in HDN33 neuroblastoma cells to determine synergistic drug combinations t...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_HDN33
Name: Drug screen in HD-MB03 medulloblastoma cells to determine synergistic drug combinatio...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_HD-MB03
Name: Drug screen in CRL2098 osteosarcoma cells to determine synergistic drug combinations ...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_CRL2098
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: A screen for compounds that inhibit viral RNA polymerase binding and polymerization a...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: Chain A, Poliovirus Polymerase With Gtp
External Id: HMS750
Name: Drug screen in CRL1545 osteosarcoma cells to determine synergistic drug combinations ...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_CRL1545
Name: Drug screen in LFS_MB_2R medulloblastoma cells to determine synergistic drug combinat...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_LFS_MB_2R
Name: Drug screen in UWB1.289 ovarian carcinoma cells to determine synergistic drug combina...
Source: 25008
Target: N/A
External Id: DKFZ_drug_screen_chromothripsis_UWB1.289
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 Synonyms

5,6-Dihydrothymine
5-Methyl-dihydro-pyrimidin-2,4-dion
5,6-Dihydro-5-methyl-2,4-dioxypyrimidine
Hydrouracil,5-methyl
5-methyl-hydrouracil
5-Methyl-5,6-dihydrouracil
5,6-Dihydro-5-methyluracil
Dihydrothymine
5-methyl-1,3-diazinane-2,4-dione
5-methyl-dihydro-pyrimidine-2,4-dione
EINECS 211-787-7
MFCD00023159
5-methyl-dihydrouracil
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