Esculentoside H

Modify Date: 2024-01-04 16:45:30

Esculentoside H Structure
Esculentoside H structure
 Common Name Esculentoside H
CAS Number 66656-92-6 Molecular Weight 989.104
Density 1.5±0.1 g/cm3 Boiling Point 1042.8±65.0 °C at 760 mmHg
Molecular Formula C48H76O21 Melting Point N/A
MSDS N/A Flash Point 295.3±27.8 °C

 Use of Esculentoside H


Esculentoside H (EsH) is a water-soluble saponin isolated and purified from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2].Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].

 Names

Name 1-O-[(2β,3β,5ξ,18α)-3-{[4-O-(β-D-Glucopyranosyl)-β-D-xylopyranosyl]oxy}-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-β-D-glucopyranose
Synonym More Synonyms

 Esculentoside H Biological Activity

Description Esculentoside H (EsH) is a water-soluble saponin isolated and purified from the root extract of perennial plant Phytolacca esculenta[1]. Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease[2].Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression[1].
Related Catalog
References

[1]. Ha SH, et al. Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP-9 gene expression via NF-kB signaling pathway. J Cell Biochem. 2019 Jun;120(6):9810-9819.

[2]. Hu ZL, et al. Effect of esculentoside H on release of tumor necrosis factor from mouse peritoneal macrophages. Zhongguo Yao Li Xue Bao. 1993 Nov;14(6):550-2.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 1042.8±65.0 °C at 760 mmHg
Molecular Formula C48H76O21
Molecular Weight 989.104
Flash Point 295.3±27.8 °C
Exact Mass 988.487915
LogP 1.78
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.635

 Synonyms

β-D-Glucopyranose, 1-O-[(2β,3β,5ξ,18α)-3-[(4-O-β-D-glucopyranosyl-β-D-xylopyranosyl)oxy]-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-
1-O-[(2β,3β,5ξ,18α)-3-{[4-O-(β-D-Glucopyranosyl)-β-D-xylopyranosyl]oxy}-2,23-dihydroxy-29-methoxy-28,29-dioxoolean-12-en-28-yl]-β-D-glucopyranose
Esculentoside H
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Chemsrc provides Esculentoside H(CAS#:66656-92-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Esculentoside H are included as well.>> amp version: Esculentoside H

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