Esculin sesquihydrate

Modify Date: 2024-01-02 11:45:19

Esculin sesquihydrate Structure
Esculin sesquihydrate structure
 Common Name Esculin sesquihydrate
CAS Number 66778-17-4 Molecular Weight 367.31
Density 0.791 g/mL at 20 °C Boiling Point N/A
Molecular Formula C15H16O9.3/2H2O Melting Point 203-205 °C
MSDS N/A Flash Point N/A

 Use of Esculin sesquihydrate


Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway[1][2].

 Names

Name Esculin Sesquihydrate
Synonym More Synonyms

 Esculin sesquihydrate Biological Activity

Description Esculin sesquihydrate, a fluorescent coumarin glucoside, is an active ingredient of ash bark. Esculin sesquihydrate ameliorates cognitive impairment in experimental diabetic nephropathy (DN), and exerts anti?oxidative stress and anti?inflammatory effects, via the MAPK signaling pathway[1][2].
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References

[1]. Knox K, et al. The Coumarin Glucoside, Esculin, Reveals Rapid Changes in Phloem-Transport Velocity in Response to Environmental Cues. Plant Physiol. 2018 Oct;178(2):795-807.  

[2]. Song Y, et al. Esculin ameliorates cognitive impairment in experimental diabetic nephropathy and induces anti-oxidative stress and anti-inflammatory effects via the MAPK pathway. Mol Med Rep. 2018 May;17(5):7395-7402.  

 Chemical & Physical Properties

Density 0.791 g/mL at 20 °C
Melting Point 203-205 °C
Molecular Formula C15H16O9.3/2H2O
Molecular Weight 367.31
Exact Mass 358.089996
PSA 159.05000

 Safety Information

Hazard Codes F;C
Risk Phrases 11-20/21/22-34-68/20/21/22-36/37/38
Safety Phrases 26-36/37/39-45-36/37
RIDADR UN 2924 3/PG 2
WGK Germany 3.0

 Synonyms

7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
MFCD00149492
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-, hydrate (1:1)
EINECS 208-517-5
7-hydroxy-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one,hydrate
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Chemsrc provides Esculin sesquihydrate(CAS#:66778-17-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Esculin sesquihydrate are included as well.>> amp version: Esculin sesquihydrate

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