DSS Crosslinker
DSS Crosslinker structure
|
Common Name | DSS Crosslinker | ||
|---|---|---|---|---|
| CAS Number | 68528-80-3 | Molecular Weight | 368.339 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 513.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C16H20N2O8 | Melting Point | 169-170ºC | |
| MSDS | Chinese USA | Flash Point | 264.4±32.9 °C | |
Use of DSS CrosslinkerDSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | disuccinimidyl suberate |
|---|---|
| Synonym | More Synonyms |
| Description | DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 513.5±60.0 °C at 760 mmHg |
| Melting Point | 169-170ºC |
| Molecular Formula | C16H20N2O8 |
| Molecular Weight | 368.339 |
| Flash Point | 264.4±32.9 °C |
| Exact Mass | 368.121979 |
| PSA | 127.36000 |
| LogP | -2.24 |
| Appearance of Characters | powder |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.555 |
| Storage condition | 2-8°C |
| Water Solubility | chloroform: 50 mg/mL | Insoluble in water. Soluble in chloroform: 50 mg/mL. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29171900 |
|
~80%
DSS Crosslinker CAS#:68528-80-3 |
| Literature: Van Den Berg, Tieme A.; Feringa, Ben L.; Roelfes, Gerard Chemical Communications, 2007 , # 2 p. 180 - 182 |
| Precursor 2 | |
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| DownStream 0 | |
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Stability of structured Kaposi's sarcoma-associated herpesvirus ORF57 protein is regulated by protein phosphorylation and homodimerization.
J. Virol. 89(6) , 3256-74, (2015) Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 plays an essential role in KSHV lytic infection by promoting viral gene expression at the posttranscriptional level. Using bioinformatic and bioche... |
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Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone.
Nat. Commun. 6 , 6123, (2015) The chaperones Ump1 and Pba1-Pba2 promote efficient biogenesis of 20S proteasome core particles from its subunits via 15S intermediates containing alpha and beta subunits, except beta7. Here we elucid... |
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Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptor.
Br. J. Pharmacol. 172(2) , 593-605, (2014) Naturally occurring single-nucleotide polymorphisms (SNPs) within GPCRs can result in alterations in various pharmacological parameters. Understanding the regulation and function of endocytic traffick... |
| 1,1'-((1,8-Dioxo-1,8-octanediyl)bis(oxy))bis-2,5-pyrrolidinedione |
| 1,1'-[(1,8-Dioxo-1,8-octanediyl)bis(oxy)]di(2,5-pyrrolidinedione) |
| Di(N-succinimidyl) Suberate |
| 2,5-Pyrrolidinedione, 1,1'-((1,8-dioxo-1,8-octanediyl)bis(oxy))bis- |
| Disuccinimidyl octanedioate |
| Suberic acid bis(N-succinimidyl) ester |
| MFCD00049059 |
| 1,1'-[(1,8-Dioxooctane-1,8-diyl)bis(oxy)]dipyrrolidine-2,5-dione |
| Disuccinimidyl suberate |
| Suberic acid bis(N-hydroxysuccinimide ester) |
| 2,5-Pyrrolidinedione, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis- |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: DSS Crosslinker
- Price: Check
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- Delivery: 10 Day
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: DSS Crosslinker
- Price: ￥298.0/1g
- Purity: 98.0%
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- DC Chemicals Limited
- China
- Product Name: DSS Crosslinker
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Disuccinimidyl suberate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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