Eledoisin acetate salt

Modify Date: 2025-08-20 16:47:32

Eledoisin acetate salt Structure
Eledoisin acetate salt structure
Common Name Eledoisin acetate salt
CAS Number 69-25-0 Molecular Weight 1188.396
Density 1.3±0.1 g/cm3 Boiling Point 1618.1±65.0 °C at 760 mmHg
Molecular Formula C54H85N13O15S Melting Point N/A
MSDS N/A Flash Point 932.4±34.3 °C

 Use of Eledoisin acetate salt


Eledoisin is a specific agonist of NK2 and NK3 receptors. Sequence: {Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.

 Names

Name Eledoisin
Synonym More Synonyms

 Eledoisin acetate salt Biological Activity

Description Eledoisin is a specific agonist of NK2 and NK3 receptors. Sequence: {Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2.
Related Catalog
Target

NK2 and NK3 receptors[1].

In Vitro Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P < 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively[1].
In Vivo Eledoisin (0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].
References

[1]. Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5.

[2]. Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1618.1±65.0 °C at 760 mmHg
Molecular Formula C54H85N13O15S
Molecular Weight 1188.396
Flash Point 932.4±34.3 °C
Exact Mass 1187.600830
PSA 463.25000
LogP -1.36
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.569
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JX8688000
CHEMICAL NAME :
Eledoisin
CAS REGISTRY NUMBER :
69-25-0
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C54-H85-N13-O15-S
MOLECULAR WEIGHT :
1188.58

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
300 ug/kg
TOXIC EFFECTS :
Cardiac - other changes Vascular - BP lowering not characterized in autonomic section
REFERENCE :
EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 18,58,1962

 Safety Information

WGK Germany 3
RTECS JX8688000

 Synonyms

5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-α-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide
PGLU-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
ELEDOSIN
GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
PYR-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
eledonepeptide
5-Oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-L-methioninamide
Eledone peptide
L-methioninamide, 5-oxo-L-prolyl-L-prolyl-L-seryl-L-lysyl-L-α-aspartyl-L-alanyl-L-phenylalanyl-L-isoleucylglycyl-L-leucyl-
pEPSKDAFIGLM-NH2
FI 6225 TF/Ocoa
5-Oxo-L-Pro-L-Pro-L-Ser-L-Lys-L-Asp-L-Ala-L-Phe-L-Ile-Gly-L-Leu-L-Met-NH2
PYR-PSKDAFIGLM-NH2
eledoisin
Eledoisin Acetate
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

Eledoisin acetate salt suppliers


Price: $141/10mM*1mLinWater

Reference only. check more Eledoisin acetate salt price