8-(2-Octyl-1-cyclopropen-1-yl)octanoic acid
Modify Date: 2024-01-05 11:55:36
8-(2-Octyl-1-cyclopropen-1-yl)octanoic acid structure
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Common Name | 8-(2-Octyl-1-cyclopropen-1-yl)octanoic acid | ||
|---|---|---|---|---|
| CAS Number | 738-87-4 | Molecular Weight | 294.472 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 418.7±24.0 °C at 760 mmHg | |
| Molecular Formula | C19H34O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 315.4±18.0 °C | |
Use of 8-(2-Octyl-1-cyclopropen-1-yl)octanoic acidSterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1]. |
| Name | sterculic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1]. |
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| Related Catalog | |
| Target |
delta-9 desaturase:0.9 μM (IC50) |
| In Vitro | Sterculic acid (SA) is a cyclopropene fatty acid originally found in the seeds of the plant Sterculia foetida with numerous biological activities[2]. Sterculic acid is able to reduce adrenomedullin expression (AP, RP, APS, IML, in preparation)[2]. Sterculic acid is also able to mediate anti-inflammatory and protective effects[2]. Sterculic acid has a potent luteolytic effect in ovines by inhibition in the synthesis of progesterone, which causes luteal regression[2]. |
| In Vivo | Sterculic acid has been proposed as a potential tool for the treatment of metabolic syndrome (MS) since it inhibits the activity of the stearoyl-CoA desaturase-1 (SCD1) in vivo[3]. |
| References |
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 418.7±24.0 °C at 760 mmHg |
| Molecular Formula | C19H34O2 |
| Molecular Weight | 294.472 |
| Flash Point | 315.4±18.0 °C |
| Exact Mass | 294.255890 |
| PSA | 37.30000 |
| LogP | 7.72 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.487 |
| Hazard Codes | Xi |
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8-(2-Octyl-1-cy... CAS#:738-87-4 |
| Literature: Tetrahedron Letters, , vol. 33, # 11 p. 1521 - 1522 |
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~%
8-(2-Octyl-1-cy... CAS#:738-87-4 |
| Literature: Tetrahedron Letters, , vol. 33, # 11 p. 1521 - 1522 |
|
~%
8-(2-Octyl-1-cy... CAS#:738-87-4 |
| Literature: Tetrahedron Letters, , vol. 33, # 11 p. 1521 - 1522 |
CAS#:3220-60-8| 1-Cyclopropene-1-octanoic acid, 2-octyl- |
| Sterculia-Saeure |
| Sterculinic acid |
| Poly-saeure: <C19H34O2>x |
| 9,10-methylene-9-octadecenoic acid |
| 8-(2-octylcyclopropen-1-yl)octanoic acid |
| 8-(2-Octyl-1-cyclopropen-1-yl)octanoic acid |
| Sterculinsaeure |
| Sterculic-saeure |