AI-1
AI-1 structure
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Common Name | AI-1 | ||
|---|---|---|---|---|
| CAS Number | 75483-04-4 | Molecular Weight | 265.69200 | |
| Density | 1.34g/cm3 | Boiling Point | 358.7ºC at 760 mmHg | |
| Molecular Formula | C13H12ClNO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 170.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of AI-1Nrf2 acticatior AI-1 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1, activates an ARE-dependent luciferase reporter with an EC50 of 2.7 uM. |
| Name | ethyl 4-chloro-1-methyl-2-oxoquinoline-3-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Density | 1.34g/cm3 |
|---|---|
| Boiling Point | 358.7ºC at 760 mmHg |
| Molecular Formula | C13H12ClNO3 |
| Molecular Weight | 265.69200 |
| Flash Point | 170.7ºC |
| Exact Mass | 265.05100 |
| PSA | 48.30000 |
| LogP | 2.36860 |
| Index of Refraction | 1.597 |
| InChIKey | XUJQDJGGHFNYDY-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1c(Cl)c2ccccc2n(C)c1=O |
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~87%
AI-1 CAS#:75483-04-4 |
| Literature: Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054 |
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AI-1 CAS#:75483-04-4 |
| Literature: Ismaili, Lhassane; Refouvelet, Bernard; Robert, Jean Francois Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 719 - 722 |
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~%
AI-1 CAS#:75483-04-4 |
| Literature: Ismaili, Lhassane; Refouvelet, Bernard; Robert, Jean Francois Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 719 - 722 |
|
~%
AI-1 CAS#:75483-04-4 |
| Literature: Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054 |
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Genome-wide RNA sequencing analysis of quorum sensing-controlled regulons in the plant-associated Burkholderia glumae PG1 strain.
Appl. Environ. Microbiol. 81 , 7993-8007, (2015) Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here d... |
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Involvement of luxS in Biofilm Formation by Capnocytophaga ochracea.
PLoS ONE 11 , e0147114, (2016) Capnocytophaga ochracea is present in the dental plaque biofilm of patients with periodontitis. Biofilm cells change their phenotype through quorum sensing in response to fluctuations in cell-populati... |
| ARE inducer-1 |
| 3-Quinolinecarboxylic acid,1,2-dihydro-4-chloro-1-methyl-2-oxo-,ethyl ester |
| ethyl 1-methyl-4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate |
| antioxidant response element inducer-1 |
| 1-methyl-2-oxo-4-chloroquinoline-3-carboxylic acid ethyl ester |
| 4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid ethyl ester |
| 4-chloro-1-methyl-2-oxoquinoline-3-carboxylic acid ethyl ester |
| ethyl 4-chloro-2-oxo-N-methyl-1,2-dihydroquinoline-3-carboxylate |
| ethyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate |