AI-1

Modify Date: 2024-01-18 18:51:36

AI-1 Structure
AI-1 structure
Common Name AI-1
CAS Number 75483-04-4 Molecular Weight 265.69200
Density 1.34g/cm3 Boiling Point 358.7ºC at 760 mmHg
Molecular Formula C13H12ClNO3 Melting Point N/A
MSDS Chinese USA Flash Point 170.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of AI-1


Nrf2 acticatior AI-1 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1, activates an ARE-dependent luciferase reporter with an EC50 of 2.7 uM.

 Names

Name ethyl 4-chloro-1-methyl-2-oxoquinoline-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.34g/cm3
Boiling Point 358.7ºC at 760 mmHg
Molecular Formula C13H12ClNO3
Molecular Weight 265.69200
Flash Point 170.7ºC
Exact Mass 265.05100
PSA 48.30000
LogP 2.36860
Index of Refraction 1.597

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
RIDADR NONH for all modes of transport

 Synthetic Route

~87%

AI-1 Structure

AI-1

CAS#:75483-04-4

Literature: Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054

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AI-1 Structure

AI-1

CAS#:75483-04-4

Literature: Ismaili, Lhassane; Refouvelet, Bernard; Robert, Jean Francois Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 719 - 722

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AI-1 Structure

AI-1

CAS#:75483-04-4

Literature: Ismaili, Lhassane; Refouvelet, Bernard; Robert, Jean Francois Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 3 p. 719 - 722

~%

AI-1 Structure

AI-1

CAS#:75483-04-4

Literature: Carrer, Amandine; Brion, Jean-Daniel; Messaoudi, Samir; Alami, Mouad Advanced Synthesis and Catalysis, 2013 , vol. 355, # 10 p. 2044 - 2054

 Articles2

More Articles
Genome-wide RNA sequencing analysis of quorum sensing-controlled regulons in the plant-associated Burkholderia glumae PG1 strain.

Appl. Environ. Microbiol. 81 , 7993-8007, (2015)

Burkholderia glumae PG1 is a soil-associated motile plant-pathogenic bacterium possessing a cell density-dependent regulation system called quorum sensing (QS). Its genome contains three genes, here d...

Involvement of luxS in Biofilm Formation by Capnocytophaga ochracea.

PLoS ONE 11 , e0147114, (2016)

Capnocytophaga ochracea is present in the dental plaque biofilm of patients with periodontitis. Biofilm cells change their phenotype through quorum sensing in response to fluctuations in cell-populati...

 Synonyms

ARE inducer-1
3-Quinolinecarboxylic acid,1,2-dihydro-4-chloro-1-methyl-2-oxo-,ethyl ester
ethyl 1-methyl-4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
antioxidant response element inducer-1
1-methyl-2-oxo-4-chloroquinoline-3-carboxylic acid ethyl ester
4-Chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylic acid ethyl ester
4-chloro-1-methyl-2-oxoquinoline-3-carboxylic acid ethyl ester
ethyl 4-chloro-2-oxo-N-methyl-1,2-dihydroquinoline-3-carboxylate
ethyl 4-chloro-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: AI-1
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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