b-Neo-Endorphin
Modify Date: 2024-01-08 23:02:35
b-Neo-Endorphin structure
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Common Name | b-Neo-Endorphin | ||
|---|---|---|---|---|
| CAS Number | 77739-21-0 | Molecular Weight | 1100.27000 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C54H77N13O12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of b-Neo-Endorphinβ-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9[1][2]. |
| Name | β-Neoendorphin |
|---|---|
| Synonym | More Synonyms |
| Description | β-Neo-Endorphin is an endogenous opioid peptide. β-Neo-Endorphin is a hypothalamic “big” Leu-enkephalin of porcine origin. β-Neo-Endorphin shows activation of the Erk1/2, MMP-2 and MMP-9[1][2]. |
|---|---|
| Related Catalog | |
| Target |
ERK1 ERK2 MMP-2 MMP-9 |
| In Vitro | β-Neo-Endorphin (0-20 μM, 20 h) stimulates wound healing in human keratinocytes[2]. β-Neo-Endorphin (promotes wound healing through activation of the Erk1/2 signaling pathway in human keratinocytes[2]. β-Neo-Endorphin (0-20 μM, 12 h) stimulates keratinocyte migration through activation of metalloproteinase (MMP)-2 and -9[2]. β-Neo-Endorphin (12 h) stimulates migration in the fibroblast[2]. Cell Viability Assay[2] Cell Line: Human keratinocytes (HaCaT) Concentration: 0, 5, 10 and 20 μM Incubation Time: 20 h Result: Significantly increased the wound closure. Had no observable effect on cell viability. Western Blot Analysis[2] Cell Line: Human keratinocytes (HaCaT) Concentration: 0, 5, 10 and 20 μM Incubation Time: 12 h Result: Activated Erk1/2, phosphorylated P90RSK and Elk-1, showed significant upregulation of MMP-2 and -9 expression. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C54H77N13O12 |
| Molecular Weight | 1100.27000 |
| Exact Mass | 1099.58000 |
| PSA | 418.21000 |
| LogP | 1.59 |
| Index of Refraction | 1.653 |
| L-Proline, L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithyl-L-lysyl-L-tyrosyl- |
| L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N-(diaminomethylene)-L-ornithyl-L-lysyl-L-tyrosyl-L-proline |
| β-Neoendorphin |
| β-neo-endorphin |
| b-Neo-Endorphin |
- GL Biochem (Shanghai) Ltd.
- China
- Product Name: b-Neo-Endorphin
- Price: $Inquiry/1g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Jackie Yang
- Taiwan Oyi peptide Co. Ltd
- China
- Product Name: b-Neo-Endorphin
- Price: $Inquiry/1mg $Inquiry/100kg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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