7-Epi-10-deacetyltaxol

Modify Date: 2024-01-13 01:28:48

7-Epi-10-deacetyltaxol Structure
7-Epi-10-deacetyltaxol structure
Common Name 7-Epi-10-deacetyltaxol
CAS Number 78454-17-8 Molecular Weight 811.86900
Density 1.41±0.1 g/cm3 (20 ºC 760 Torr) Boiling Point 959.5℃ at 760 mmHg
Molecular Formula C45H49NO13 Melting Point 163-170?C
MSDS N/A Flash Point N/A

 Use of 7-Epi-10-deacetyltaxol


7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM[1][2].

 Names

Name 10-deacetyltaxol
Synonym More Synonyms

 7-Epi-10-deacetyltaxol Biological Activity

Description 7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM[1][2].
Related Catalog
References

[1]. Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2).

[2]. Dang PH, et al.α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana. J Nat Prod. 2017 Apr 28;80(4):1087-1095.

 Chemical & Physical Properties

Density 1.41±0.1 g/cm3 (20 ºC 760 Torr)
Boiling Point 959.5℃ at 760 mmHg
Melting Point 163-170?C
Molecular Formula C45H49NO13
Molecular Weight 811.86900
Exact Mass 811.32000
PSA 218.71000
LogP 3.73970
Storage condition -20°C Freezer, Under Inert Atmosphere
Water Solubility Insuluble (2.4E-4 g/L) (25 ºC)

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synonyms

Ormosin VI
10-Desacetyl-7-epipaclitaxel
10-Deacetyl-7-epi-taxol
7-Epi-10-deacetyltaxol
7-Epi 10-Desacetyl Paclitaxel
CS-1143
10-Deacetyl-7-epi-paclitaxel
7-Epi-10-deacetyl-taxol
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