m-PEG4-sulfonic acid

Modify Date: 2024-01-10 21:52:57

m-PEG4-sulfonic acid Structure
m-PEG4-sulfonic acid structure
Common Name m-PEG4-sulfonic acid
CAS Number 787524-78-1 Molecular Weight 272.316
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C9H20O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-sulfonic acid


m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG4-sulfonic acid
Synonym More Synonyms

 m-PEG4-sulfonic acid Biological Activity

Description m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C9H20O7S
Molecular Weight 272.316
Exact Mass 272.092987
LogP -2.95
Index of Refraction 1.464

 Synonyms

MFCD29042380
2,5,8,11-Tetraoxatridecane-13-sulfonic acid
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