Amino-PEG2-C2-acid

Modify Date: 2024-01-13 10:36:20

Amino-PEG2-C2-acid Structure
Amino-PEG2-C2-acid structure
Common Name Amino-PEG2-C2-acid
CAS Number 791028-27-8 Molecular Weight 177.198
Density 1.1±0.1 g/cm3 Boiling Point 331.5±27.0 °C at 760 mmHg
Molecular Formula C7H15NO4 Melting Point N/A
MSDS N/A Flash Point 154.3±23.7 °C

 Use of Amino-PEG2-C2-acid


Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name 3-[2-(2-Aminoethoxy)ethoxy]propanoic acid
Synonym More Synonyms

 Amino-PEG2-C2-acid Biological Activity

Description Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Antibody drug conjugate, intermediate, preparation method, pharmaceutical composition and uses thereof. WO2016197946A1.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 331.5±27.0 °C at 760 mmHg
Molecular Formula C7H15NO4
Molecular Weight 177.198
Flash Point 154.3±23.7 °C
Exact Mass 177.100113
LogP -1.21
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.467
Storage condition 2-8°C

 Synonyms

Propanoic acid, 3-[2-(2-aminoethoxy)ethoxy]-
3-[2-(2-Aminoethoxy)ethoxy]propanoic acid
H2N-PEG2-COOH
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