Gastric mucin structure
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Common Name | Gastric mucin | ||
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CAS Number | 84082-64-4 | Molecular Weight | N/A | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | N/A | Melting Point | N/A | |
MSDS | USA | Flash Point | N/A |
Use of Gastric mucinGastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. |
Name | Gastron |
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Synonym | More Synonyms |
Description | Gastric mucin is a large glycoprotein which is thought to play a major role in the protection of the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. |
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Related Catalog | |
In Vitro | Gastric mucin may be integrally involved in the mechanism of gastric mucosal injury caused by Helicobacter pylori leading to gastritis, peptic ulceration, and possibly gastric cancer[1]. Gastric mucins are classified into two types based on their histochemical properties. The first is a surface mucous cell-type mucin, secreted from the surface mucous cells. The second is found in deeper portions of the mucosa and is secreted by gland mucous cells, including mucous neck cells, cardiac gland cells, and pyloric gland cells. The unique O-glycans in gastric mucin appears to function as a natural antibiotic, protecting the host from H. pylori infection[2]. Gastric mucin may provide protection to the surface epithelium gastrointestinal tract by scavenging oxidants produced within the lumen; however, it does so at the expense of its viscoelastic properties. Both native and pronase-treated mucin effectively scavenge hydroxyl radical and that the scavenging properties are not significantly different. The effective concentration of mucin required for a 50% reduction in malondialdehyde production is 10 mg/mL for both native and pronase-treated mucin[3]. |
References |
Appearance of Characters | partially purified powder |
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Storage condition | 2-8°C |
Water Solubility | 1 M NaOH: soluble20mg/mL |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
Oral bioaccessibility of arsenic, mercury and methylmercury in marine species commercialized in Catalonia (Spain) and health risks for the consumers.
Food Chem. Toxicol. 86 , 34-40, (2015) This study was aimed at characterizing the bioaccessibility of arsenic (As), mercury (Hg) and methylmercury (MeHg) in commercial fish and seafood species widely consumed by the population of Catalonia... |
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Characterization of novel beta-galactosidase activity that contributes to glycoprotein degradation and virulence in Streptococcus pneumoniae.
Infect. Immun. 78(1) , 348-57, (2010) The pneumococcus obtains its energy from the metabolism of host glycosides. Therefore, efficient degradation of host glycoproteins is integral to pneumococcal virulence. In search of novel pneumococca... |
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Effect of broccoli phytochemical extract on release of fatty acids from salmon muscle and salmon oil during in vitro digestion.
Food Funct. 5(9) , 2331-7, (2014) The aim of the present work was to study the effect of a broccoli phytochemical extract (Br-ex) on the release of fatty acids (FA) from salmon muscle (SM) and salmon oil (SO) during in vitro digestion... |
Gastric Mucin |
EINECS 282-010-7 |