t-Boc-N-amido-PEG5-acetic acid

Modify Date: 2024-01-21 11:16:21

t-Boc-N-amido-PEG5-acetic acid Structure
t-Boc-N-amido-PEG5-acetic acid structure
Common Name t-Boc-N-amido-PEG5-acetic acid
CAS Number 890152-41-7 Molecular Weight 395.45
Density N/A Boiling Point N/A
Molecular Formula C17H33NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-N-amido-PEG5-acetic acid


BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name BocNH-PEG5-acid
Synonym More Synonyms

 t-Boc-N-amido-PEG5-acetic acid Biological Activity

Description BocNH-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Molecular Formula C17H33NO9
Molecular Weight 395.45

 Synonyms

2,2-Dimethyl-4-oxo-3,8,11,14,17,20-hexaoxa-5-azadocosan-22-oic acid, Boc-NH-PEG5-CH2COOH
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