β-LactaMase

Modify Date: 2024-01-03 14:57:18

β-LactaMase Structure
β-LactaMase structure
Common Name β-LactaMase
CAS Number 9073-60-3 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

 Use of β-LactaMase


β-Lactamase is the enzyme produced by bacteria. β-Lactamase mediates β-lactam resistance[1].

 Names

Name β-Lactamase
Synonym More Synonyms

 β-LactaMase Biological Activity

Description β-Lactamase is the enzyme produced by bacteria. β-Lactamase mediates β-lactam resistance[1].
Related Catalog
In Vitro 在革兰氏阴性菌中,水解四元 β-内酰胺环的酰胺键是 β-Lactamase 主要的耐药机制,多种酶散布在机会致病菌:肠杆菌科 (如大肠杆菌) 和非发酵生物 (如铜绿假单胞菌) 的移动遗传元件上。β-Lactamase 分为四类:活性位点丝氨酸 β-Lactamase (A、C 和 D 类) 和锌依赖性或金属 β-Lactamase (MBLs; B 类)[1]。
References

[1]. Tooke CL, et al. β-Lactamases and β-Lactamase Inhibitors in the 21st Century. J Mol Biol. 2019 Aug 23;431(18):3472-3500.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H317-H334
Precautionary Statements P261-P280-P342 + P311
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn
RIDADR NONH for all modes of transport
WGK Germany 3.0
RTECS OD2265000

 Articles69

More Articles
A Novel Microbisporicin Producer Identified by Early Dereplication during Lantibiotic Screening.

Biomed Res. Int. 2015 , 419383, (2015)

With the increasing need of effective antibiotics against multi-drug resistant pathogens, lantibiotics are an attractive option of a new class of molecules. They are ribosomally synthetized and posttr...

Identification of peptide inhibitors of penicillinase using a phage display library.

Anal. Biochem. 494 , 4-9, (2015)

There is a constant need to identify novel inhibitors to combat β-lactamase-mediated antibiotic resistance. In this study, we identify three penicillinase-binding peptides, P1 (DHIHRSYRGEFD), P2 (NIYT...

Outbreak of PER-1 and diversity of β-lactamases among ceftazidime-resistant Pseudomonas aeruginosa clinical isolates.

J. Med. Microbiol. 63(Pt 3) , 386-92, (2014)

A growing number of β-lactamases have been reported in Pseudomonas aeruginosa clinical isolates. The aim of this study was to investigate the diversity of β-lactamases in the collection of 51 ceftazid...

 Synonyms

MFCD00131819
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