Metallo-β-lactamase-IN-7
Modify Date: 2024-01-09 14:21:36
Metallo-β-lactamase-IN-7 structure
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Common Name | Metallo-β-lactamase-IN-7 | ||
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| CAS Number | 2752453-58-8 | Molecular Weight | 274.30 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H10N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Metallo-β-lactamase-IN-7Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains[1]. |
| Name | Metallo-β-lactamase-IN-7 |
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| Description | Metallo-β-lactamase-IN-7 is a potent VIM-Type metallo-β-lactamase inhibitor with IC50s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5. Metallo-β-lactamase-IN-7 potentiate antibacterial activity of Meropenem against the Gram-negative bacterial strains[1]. |
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| Related Catalog | |
| Target |
IC50: 0.019 μM (VIM-2), 13.64 μM (VIM-1), 0.38 μM (VIM-5)[1] |
| In Vitro | Metallo-β-lactamase-IN-7 (compound 59) (10 μM; 18 - 20 hours) can potentiate Meropenem activity against VIM-2 mediated antibacterial resistance with FIC index values of 0.02[1]. Metallo-β-lactamase-IN-7 (100 μM) potentiates the antibacterial activity of Meropenem against PA W35 with FIC index values of 0.125[1]. |
| References |
| Molecular Formula | C12H10N4O2S |
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| Molecular Weight | 274.30 |