2-Hydroxybenzylamine

Modify Date: 2025-08-25 20:00:19

2-Hydroxybenzylamine Structure
2-Hydroxybenzylamine structure
 Common Name 2-Hydroxybenzylamine
CAS Number 932-30-9 Molecular Weight 123.152
Density 1.1±0.1 g/cm3 Boiling Point 245.0±15.0 °C at 760 mmHg
Molecular Formula C7H9NO Melting Point 127-131ºC
MSDS Chinese USA Flash Point 102.0±20.4 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Use of 2-Hydroxybenzylamine


o-Hydroxybenzylamine (2-HOBA) a selective dicarbonyl scavenger, is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). o-Hydroxybenzylamine can be used in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias[1][2].

 Names

Name 2-(Aminomethyl)phenol
Synonym More Synonyms

 2-Hydroxybenzylamine Biological Activity

Description o-Hydroxybenzylamine (2-HOBA) a selective dicarbonyl scavenger, is an antioxidant and scavanger of free radicals and isolevuglandins (IsoLGs). o-Hydroxybenzylamine can be used in the research of inflammation and cardiovascular disease, such as atherosclerosis, early recurrence of atrial fibrillation (AF) and arrhythmias[1][2].
Related Catalog
References

[1]. Matthew J O'Neill, et al. 2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device.

[2]. Huan Tao, et al. Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr -/- mice.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 245.0±15.0 °C at 760 mmHg
Melting Point 127-131ºC
Molecular Formula C7H9NO
Molecular Weight 123.152
Flash Point 102.0±20.4 °C
Exact Mass 123.068413
PSA 46.25000
LogP 0.35
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.594
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S37/39
RIDADR NONH for all modes of transport
HS Code 2922299090

 Synthetic Route

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

EINECS 213-249-7
Phenol, 2-(aminomethyl)-
2-(Aminomethyl)phenol
2-Hydroxybenzylamine
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