BAL-30072

Modify Date: 2024-01-10 18:34:09

BAL-30072 Structure
BAL-30072 structure
Common Name BAL-30072
CAS Number 941285-15-0 Molecular Weight 518.47800
Density N/A Boiling Point N/A
Molecular Formula C16H18N6O10S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAL-30072


BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2].

 Names

Name [(3S)-3-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1,5-dihydroxy-4-oxopyridin-2-yl)methoxyimino]acetyl]amino]-2,2-dimethyl-4-oxoazetidin-1-yl] hydrogen sulfate
Synonym More Synonyms

 BAL-30072 Biological Activity

Description BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli. BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2].
Related Catalog
Target

MIC90: 4 μg/mL (MDR Acinetobacter spp.), 8 μg/mL (MDR P. aeruginosa)[1][2].

References

[1]. Page MG, et al. In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli. Antimicrob Agents Chemother. 2010 Jun;54(6):2291-302.

[2]. Michael Hornsey, et al. In vitro activity of the novel monosulfactam BAL30072 alone and in combination with meropenem versus a diverse collection of important Gram-negative pathogens. Int J Antimicrob Agents. 2013 Oct;42(4):343-6.

 Chemical & Physical Properties

Molecular Formula C16H18N6O10S2
Molecular Weight 518.47800
Exact Mass 518.05300
PSA 276.81000
LogP 0.37990

 Synonyms

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