Maleimide-PEG2-NHS Ester

Modify Date: 2024-01-08 12:59:28

Maleimide-PEG2-NHS Ester structure	Common Name	Maleimide-PEG2-NHS Ester
	CAS Number	955094-26-5	Molecular Weight	425.39000
	Density	1.41±0.1 g/cm3 (20 °C, 760 mmHg)	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₃N₃O₉	Melting Point	90.0 to 94.0 °C
	MSDS	Chinese USA	Flash Point	N/A

Use of Maleimide-PEG2-NHS Ester

Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Name	Propanoic acid, 3-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
Synonym	More Synonyms

Description	Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].
Related Catalog	Research Areas >> Others
Target	Noncleavable
References	[1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145. [2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A

Density	1.41±0.1 g/cm3 (20 °C, 760 mmHg)
Melting Point	90.0 to 94.0 °C
Molecular Formula	C₁₈H₂₃N₃O₉
Molecular Weight	425.39000
Exact Mass	425.14300
PSA	148.62000
Storage condition	20°C
Water Solubility	Slightly soluble (5.1 g/L) (25 ºC)