RAF mutant-IN-1

Modify Date: 2024-01-05 18:30:41

RAF mutant-IN-1 structure	Common Name	RAF mutant-IN-1
	CAS Number	2340020-82-6	Molecular Weight	567.85
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₁₈Cl₃FN₆O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of RAF mutant-IN-1

RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].

Name	RAF mutant-IN-1

Description	RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF 340D/Y341D, B-RAFV600E and B-RAFWT, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> Raf
Target	C-RAF 340D/Y341D:21 nM (IC50) B-RafV600E:30 nM (IC50) BRAFWT:392 nM (IC50)
References	[1]. BAE, In Hwan, et al. Title of Invention: THIENO[3,2-d]PYRIMIDINE COMPOUND HA VING INHIBITORY ACTIVITY FOR PROTEIN KINASE. WO2019107987A1.

Molecular Formula	C₂₃H₁₈Cl₃FN₆O₂S
Molecular Weight	567.85