CXCR4 modulator-2
Modify Date: 2024-01-16 17:15:05
CXCR4 modulator-2 structure
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Common Name | CXCR4 modulator-2 | ||
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| CAS Number | 2488943-55-9 | Molecular Weight | 428.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H32N8O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CXCR4 modulator-2CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1]. |
| Name | CXCR4 modulator-2 |
|---|
| Description | CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1]. |
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| Related Catalog | |
| Target |
CXCR4:1.25 nM (IC50) |
| In Vivo | CXCR4 modulator-2 (10 mg/kg; IP; single dosage) significantly reduces the edema weights (∼50%) in the lesion and decreases the expression of CXCR4s[1]. Animal Model: male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)[1] Dosage: 10 mg/kg Administration: IP; single dosage Result: Significantly reduced the edema weights (∼50%) in the lesion and decreased the expression of CXCR4s. |
| References |
| Molecular Formula | C21H32N8O2 |
|---|---|
| Molecular Weight | 428.53 |