Pyridoxine-d5 hydrochloride

Modify Date: 2024-01-14 19:49:54

Pyridoxine-d5 hydrochloride Structure
Pyridoxine-d5 hydrochloride structure
Common Name Pyridoxine-d5 hydrochloride
CAS Number 82896-38-6 Molecular Weight 205.63900
Density N/A Boiling Point N/A
Molecular Formula C8H12ClNO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pyridoxine-d5 hydrochloride


Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].

 Names

Name 3,4-Pyridinedimethan-α3,α3-d2-ol, 5-hydroxy-6-(methyl-d3)-, hydrochloride
Synonym More Synonyms

 Pyridoxine-d5 hydrochloride Biological Activity

Description Pyridoxine-d5 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride[1]. Pyridoxine hydrochloride (Pyridoxol;Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol;Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Li C, et al. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway. Cell Mol Biol (Noisy-le-grand). 2018 Jul 30;64(10):119-124.  

 Chemical & Physical Properties

Molecular Formula C8H12ClNO3
Molecular Weight 205.63900
Exact Mass 205.05100
PSA 73.58000
LogP 0.88220

 Synonyms

Pyridoxine Hydrochloride D5