< 生产厂家价格 >

柠檬苦素

柠檬苦素用途

Limonin为柑橘类水果中富含的三萜类化合物,具有抗病毒和抗肿瘤活性。

点击显示

柠檬苦素名称

[ CAS 号 ]:
1180-71-8

[ 中文名 ]:
柠檬苦素

[ 英文名 ]:
Limonin

[中文别名 ]:

[英文别名 ]:

Limonoic acid di-δ-lactone
Limonoic acid 3,19:16,17 dilactone
LiMone
DICTAMNOLACTONE
CITROLIMONIN
Limonin
Evodine
Limonoic Acid Di-d-lactone
LIMONINE
EVODIN

柠檬苦素生物活性

[ 描述 ]:

Limonin为柑橘类水果中富含的三萜类化合物,具有抗病毒和抗肿瘤活性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> HIV

研究领域 >> 感染

天然产物 >> 萜类化合物和糖苷

[参考文献]

[1]. Han YL, Yu HL, Li D, et al. Inhibitory effects of limonin on six human cytochrome P450 enzymes and P-glycoprotein in vitro. Toxicol In Vitro. 2011 Dec;25(8):1828-33.

[2]. Kotamballi N. Chidambara Murthy, Jayaprakasha, Vinod Kumar, et al. Citrus Limonin and Its Glucoside Inhibit Colon Adenocarcinoma Cell Proliferation through Apoptosis. J. Agric. Food Chem., 2011, 59 (6):2314-2323.

[3]. Mahmoud Zaki El-Readi, Dalia Hamdana, Nawal Farrag, et al. Inhibition of P-glycoprotein activity by limonin and other secondary metabolites from Citrus species in human colon and leukaemia cell lines. European Journal of Pharmacology. 2010,626 (2-3): 139-145.

[4]. Battinelli L, Mengoni F, Lichtner M, et al. Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells. Planta Med. 2003 Oct;69(10):910-3.

[5]. Tanaka T, Kohno H, Tsukio Y, et al. Citrus limonoids obacunone and limonin inhibit azoxymethane-induced colon carcinogenesis in rats. Biofactors. 2000;13(1-4):213-8.

[相关活性小分子]

柠檬苦素物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
668.4±55.0 °C at 760 mmHg

[ 熔点 ]:
298ºC

[ 分子式 ]:
C₂₆H₃₀O₈

[ 分子量 ]:
470.512

[ 闪点 ]:
358.0±31.5 °C

[ 精确质量 ]:
470.194061

[ PSA ]:
104.57000

[ LogP ]:
1.66

[ 外观性状 ]:
白色至略灰白色粉末

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.602

[ 储存条件 ]:
0-10°C;避免加热

[ 水溶解性 ]:
水溶性：不溶；可溶于：四氢呋喃,丙酮；极微溶：乙醚,醇

柠檬苦素MSDS

详细MSDS(安全技术说明书)

柠檬苦素安全信息

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
RR1122000

柠檬苦素上下游产品

柠檬苦素上游产品

柠檬苦素下游产品

柠檬苦素制备

植物来源有芸香科植物黄柏(Phellodendron amurense Rupr.)的皮,自鲜(Dictamnus alba L.)的皮等

点击显示

柠檬苦素文献

Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques.

J. Food Sci. 77(9) , C921-6, (2012)

Grapefruits (Citrus paradisi Macfad) contain several phytochemicals known to have health maintaining properties. Due to the consumer's interest in obtaining high levels of these phytochemicals, it is ...

Ethylene degreening modulates health promoting phytochemicals in Rio Red grapefruit.

Food Chem. 188 , 77-83, (2015)

In the current study, we examined the effects of postharvest degreening and storage on phytochemicals in Rio Red grapefruit. Grapefruits were degreened with 3.5 μl/l of ethylene at 21 °C and 80% relat...

Quinine Bitterness and Grapefruit Liking Associate with Allelic Variants in TAS2R31.

Chem. Senses 40 , 437-43, (2015)

Multiple psychophysical gene-association studies suggest a single nucleotide polymorphism (SNP) within the bitter receptor gene TAS2R19 on chromosome 12 may be functional. Previously, the Arg299Cys SN...

更多文献