乳酸丁酯

乳酸丁酯用途

【用途一】
用作溶剂，也用于油漆和油墨的配制等
【用途二】
用作医药的原料和农药中间体，也用作喷漆溶剂
【用途三】
GB 2760一9 6规定为允许使用的食用香料。主要用于配制乳制品、干酪和奶油硬糖型香精。亦可配制香荚兰、蘑菇、坚果、椰子、咖啡等香精。
【用途四】
该品为高沸点溶剂，用于天然树脂、合成树脂、香料、油漆、印刷油墨、干洗液、粘结剂。

点击显示

乳酸丁酯名称

[ CAS 号 ]:
138-22-7

[ 中文名 ]:
乳酸丁酯

[ 英文名 ]:
n-Butyl lactate

[中文别名 ]:

[英文别名 ]:

Propanoic acid, 2-hydroxy-, butyl ester
UNII:0UI63W814U
MFCD00004519
n-Butyl lactate
Lactic Acid Butyl Ester
Butyl 2-hydroxypropanoate
EINECS 205-316-4
Butyl 2-Hydroxypropionate
Butyl Lactate

乳酸丁酯物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
189.4±8.0 °C at 760 mmHg

[ 熔点 ]:
−28 °C(lit.)

[ 分子式 ]:
C₇H₁₄O₃

[ 分子量 ]:
146.184

[ 闪点 ]:
69.4±0.0 °C

[ 精确质量 ]:
146.094299

[ PSA ]:
46.53000

[ LogP ]:
0.88

[ 外观性状 ]:
一种透明无色液体带有一种温和气味

[ 蒸汽密度 ]:
5.04 (vs air)

[ 蒸汽压 ]:
0.2±0.8 mmHg at 25°C

[ 折射率 ]:
1.432

[ 储存条件 ]:
包装完整、轻装轻放,库房通风、远离明火、高温、与氧化剂分开存放

[ 水溶解性 ]:
42 g/L (25 ºC)

乳酸丁酯MSDS

乳酸丁酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD4025000

CHEMICAL NAME :: Lactic acid, butyl ester

CAS REGISTRY NUMBER :: 138-22-7

BEILSTEIN REFERENCE NO. :: 1721597

LAST UPDATED :: 199712

DATA ITEMS CITED :: 21

MOLECULAR FORMULA :: C7-H14-O3

MOLECULAR WEIGHT :: 146.21

WISWESSER LINE NOTATION :: QY1&VO4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,15,1974

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11 gm/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,727,1979 *** REVIEWS *** ACGIH TLV-TWA 30 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 ppm (5 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,33,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-BELGIUM:TWA 5 ppm (30 mg/m3) JAN 1993 OEL-DENMARK:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-FINLAND:TWA 1 ppm (6 mg/m3);STEL 3 ppm (18 mg/m3) JAN 1993 OEL-FRANCE:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (25 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (30 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (25 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO n-BUTYL LACTATE-air:10H TWA 5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1128 No. of Facilities: 242 (estimated) No. of Industries: 8 No. of Occupations: 10 No. of Employees: 3107 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1128 No. of Facilities: 170 (estimated) No. of Industries: 9 No. of Occupations: 15 No. of Employees: 5342 (estimated) No. of Female Employees: 1381 (estimated)

点击显示

乳酸丁酯安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S37/39

[ WGK德国 ]:
2

[ RTECS号 ]:
OD4025000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
2918110000

乳酸丁酯合成路线

乳酸丁酯上下游产品

乳酸丁酯上游产品

乳酸丁酯下游产品

乳酸丁酯制备

1.由乳酸与正丁醇酯化而得。酯化反应在硫酸存在下进行，反应结束后经中和、减压蒸馏而得成品。酯化反应也可以在苯或甲苯溶剂中进行。工业品乳酸丁酯的含量≥95%。原料消耗定额：乳酸（80%）1000kg/t、丁醇650kg/t。

点击显示

乳酸丁酯海关

[ 海关编码 ]: 2918110000

[ 中文概述 ]:
2918110000. 乳酸及其盐和酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2918110000. lactic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

乳酸丁酯文献

An insight on human skin penetration of diflunisal: lipogel versus hydrogel microemulsion.

Drug Dev. Ind. Pharm. 41(1) , 141-7, (2014)

Diflunisal is a NSAID used in acute and long term management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis and symptoms of primary dysmenorrhea. However, its oral use i...

Optimization, ex vivo permeation, and stability study of lipid nanocarrier loaded gelatin capsules for treatment of intermittent claudication.

Int. J. Nanomedicine 10 , 4459-78, (2015)

In this study, an optimized nanodispersible oral dosage form (containing a lactate ester) was developed for cilostazol (CZL). CZL is a phosphodiesterase inhibitor used for intermittent claudication. W...

Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique.

Int. J. Pharm. 257(1-2) , 153-60, (2003)

A preparation method for nanoparticles based on the emulsification of a butyl lactate or benzyl alcohol solution of a solid lipid in an aqueous solution of different emulsifiers, followed by dilution ...

更多文献

乳酸丁酯

乳酸丁酯用途

乳酸丁酯名称

乳酸丁酯物理化学性质

乳酸丁酯MSDS

详细MSDS(安全技术说明书)

乳酸丁酯毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

乳酸丁酯安全信息

乳酸丁酯合成路线

详细合成路线

乳酸丁酯上下游产品

乳酸丁酯上游产品

乳酸丁酯下游产品

乳酸丁酯制备

乳酸丁酯海关

乳酸丁酯文献

相关化工产品/化学物质：

推荐生产厂家/供应商：

相关化合物