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4-氨基二苯醚

4-氨基二苯醚用途

【用途一】
用作染料中间体

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4-氨基二苯醚名称

[ CAS 号 ]:
139-59-3

[ 中文名 ]:
4-氨基二苯醚

[ 英文名 ]:
4-Phenoxyaniline

[中文别名 ]:

[英文别名 ]:

4-phenoxy aniline
Benzenamine,4-phenoxy
EINECS 205-367-2
4-Aminophenyl Phenyl Ether
4-Phenoxyaniline
4-Amino-1-phenoxybenzene
p-Aminophenyl phenyl ether
4-phenoxyanilin
p-Phenoxyaniline
Aniline,p-phenoxy

4-氨基二苯醚物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
320.0±25.0 °C at 760 mmHg

[ 熔点 ]:
82-84 °C(lit.)

[ 分子式 ]:
C₁₂H₁₁NO

[ 分子量 ]:
185.222

[ 闪点 ]:
155.8±16.4 °C

[ 精确质量 ]:
185.084061

[ PSA ]:
35.25000

[ LogP ]:
2.36

[ 外观性状 ]:
棕色至绿色-棕色结晶片或粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.619

[ 储存条件 ]:
室温

[ 水溶解性 ]:
< 1 g/L (20 ºC)

4-氨基二苯醚MSDS

4-氨基二苯醚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY7930000

CHEMICAL NAME :: Aniline, p-phenoxy-

CAS REGISTRY NUMBER :: 139-59-3

BEILSTEIN REFERENCE NO. :: 0777708

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C12-H11-N-O

MOLECULAR WEIGHT :: 185.24

WISWESSER LINE NOTATION :: ZR DOR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - rat Liver

DOSE/DURATION :: 10 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 204,683,1988

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4-氨基二苯醚安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H317-H319-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22;R43;R50/53;R68

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S61-S45-S24

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
BY7930000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
2922299090

4-氨基二苯醚合成路线

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4-氨基二苯醚海关

[ 海关编码 ]: 2922299090

[ 中文概述 ]:
2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

4-氨基二苯醚文献

Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines.

Eur. J. Med. Chem. 42 , 1396-402, (2007)

Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry...

Inhibition of monoamine oxidase by selected C5- and C6-substituted isatin analogues.

Bioorg. Med. Chem. 19 , 261-74, (2011)

Previous studies have shown that (E)-5-styrylisatin and (E)-6-styrylisatin are reversible inhibitors of human monoamine oxidase (MAO) A and B. Both homologues are reported to exhibit selective binding...

Mutagenicity of nitroscanate, an antischistosomal drug.

Mutat. Res. 334(3) , 273-81, (1995)

Nitroscanate (NSC) was found to be a direct acting mutagen in the Ames Salmonella tester strains TA100 and TA98 and this activity increased further in the presence of rat liver S9 mix. It was inactive...

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