4-氯-7-羟基氢化茚
4-氯-7-羟基氢化茚用途
4-氯-7-羟基氢化茚名称
[ CAS 号 ]:
145-94-8
[ 中文名 ]:
7-氯-2,3-二氢-1H-茚-4-醇
[ 英文名 ]:
Chlorindanol
[中文别名 ]:
[英文别名 ]:
- 7-Chloro-4-indanol
- 7-Chlor-indanol-(4)
- 4-Indanol,7-chloro
- CHLORINDANOL
- Clorindanolum [INN-Latin]
- 7-Chlor-indan-4-ol
- Lanesta
- 7-chloro-indan-4-ol
- Clorindanol
4-氯-7-羟基氢化茚生物活性
[ 描述 ]:
[ 相关类别 ]:
[相关活性小分子]
4-氯-7-羟基氢化茚物理化学性质
[ 密度 ]:
1.308g/cm3
[ 沸点 ]:
290ºC at 760mmHg
[ 熔点 ]:
91-93ºC
[ 分子式 ]:
C9H9ClO
[ 分子量 ]:
168.62000
[ 闪点 ]:
129.2ºC
[ 精确质量 ]:
168.03400
[ PSA ]:
20.23000
[ LogP ]:
2.53430
[ 蒸汽压 ]:
0.00122mmHg at 25°C
[ 折射率 ]:
1.618
[ 储存条件 ]:
库房低温通风干燥
4-氯-7-羟基氢化茚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NK7533200
- CHEMICAL NAME :
- 4-Indanol, 7-chloro-
- CAS REGISTRY NUMBER :
- 145-94-8
- BEILSTEIN REFERENCE NO. :
- 1945696
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C9-H9-Cl-O
- MOLECULAR WEIGHT :
- 168.63
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 920 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,212,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 96 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,212,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,212,1959 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 8 gm/kg/5D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,212,1959
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7925 mg/kg/5D-I
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - pleural thickening Related to Chronic Data - death
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 48,212,1959
4-氯-7-羟基氢化茚安全信息
[ 危害码 (欧洲) ]:
Xi
4-氯-7-羟基氢化茚合成路线
4-氯-7-羟基氢化茚上下游产品
4-氯-7-羟基氢化茚上游产品
4-氯-7-羟基氢化茚下游产品
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：4-氯-7-羟基氢化茚
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥518.0/50mg
￥1548.0/250mg
联系人：刘佳
产品详情：4-氯-7-羟基氢化茚
公司名：上海创赛科技有限公司
区域：上海市嘉定区
价格：
￥239.0/50mg
￥719.0/250mg
联系人：夏言
产品详情：[Perfemiker]4-氯-7-羟基氢化茚,98%
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相关化合物
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