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盐酸安他唑啉

盐酸安他唑啉用途

Antazolin盐酸盐是第一代抗组胺药, 也具有抗胆碱能特性, 用于缓解鼻塞, 也用作眼药水。

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盐酸安他唑啉名称

[ CAS 号 ]:
2508-72-7

[ 中文名 ]:
盐酸安他唑啉

[ 英文名 ]:
Antazoline Hydrochloride

[中文别名 ]:

2-(N-苄基苯胺基甲基)-2-咪唑啉盐酸盐

[英文别名 ]:

Antazoline Hydrochloride
hydrochloride salt of antazoline
Antazoline HCl
UNII-FP8Q8F72JH
Fenazolina
Antistine hydrochloride
Histazine
Antazolinium chloratum
MFCD00058145
EINECS 219-719-8

盐酸安他唑啉生物活性

[ 描述 ]:

Antazolin盐酸盐是第一代抗组胺药, 也具有抗胆碱能特性, 用于缓解鼻塞, 也用作眼药水。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体

信号通路 >> 免疫及炎症 >> 组胺受体

研究领域 >> 神经疾病

[相关活性小分子]

盐酸安他唑啉物理化学性质

[ 沸点 ]:
475.5ºC at 760 mmHg

[ 熔点 ]:
238 °C

[ 分子式 ]:
C₁₇H₂₀ClN₃

[ 分子量 ]:
301.814

[ 闪点 ]:
241.4ºC

[ 精确质量 ]:
301.134583

[ PSA ]:
27.63000

[ LogP ]:
3.26130

[ 外观性状 ]:
白色或近乎于白色结晶粉末

[ 蒸汽压 ]:
3.31E-09mmHg at 25°C

[ 储存条件 ]:
Store at RT

[ 水溶解性 ]:
可溶于：甲醇

盐酸安他唑啉MSDS

详细MSDS(安全技术说明书)

盐酸安他唑啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ2150000

CHEMICAL NAME :: 2-Imidazoline, 2-((N-benzylanilino)methyl)-, hydrochloride

CAS REGISTRY NUMBER :: 2508-72-7

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H19-N3.Cl-H

MOLECULAR WEIGHT :: 301.85

WISWESSER LINE NOTATION :: T5M CN BUTJ B1NR&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 30 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - irritability Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 10,338,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 17100 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 113,313,1958

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盐酸安他唑啉安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H315-H319-H332-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R20/21/22;R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NJ2150000

[ 海关编码 ]:
2933290090

盐酸安他唑啉上下游产品

盐酸安他唑啉上游产品

盐酸安他唑啉下游产品

盐酸安他唑啉海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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