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6A-甲基-11B-羟孕酮

6A-甲基-11B-羟孕酮用途

Medrysone是皮质类固醇, 用在眼科治疗眼炎症。

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6A-甲基-11B-羟孕酮名称

[ CAS 号 ]:
2668-66-8

[ 中文名 ]:
6A-甲基-11B-羟孕酮

[ 英文名 ]:
Medrysone

[中文别名 ]:

甲羟松

[英文别名 ]:

medrysone

6A-甲基-11B-羟孕酮生物活性

[ 描述 ]:

Medrysone是皮质类固醇, 用在眼科治疗眼炎症。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[相关活性小分子]

6A-甲基-11B-羟孕酮物理化学性质

[ 密度 ]:
1.13g/cm3

[ 沸点 ]:
492.3ºC at 760mmHg

[ 分子式 ]:
C₂₂H₃₂O₃

[ 分子量 ]:
344.48800

[ 闪点 ]:
265.7ºC

[ 精确质量 ]:
344.23500

[ PSA ]:
54.37000

[ LogP ]:
3.94030

[ 外观性状 ]:
白色至灰白色粉末

[ 蒸汽压 ]:
9.3E-12mmHg at 25°C

[ 折射率 ]:
1.552

[ 储存条件 ]:
2-8℃

6A-甲基-11B-羟孕酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU5250000

CHEMICAL NAME :: Pregn-4-ene-3,20-dione, 11-beta-hydroxy-6-alpha-methyl-

CAS REGISTRY NUMBER :: 2668-66-8

LAST UPDATED :: 199504

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H32-O3

MOLECULAR WEIGHT :: 344.54

WISWESSER LINE NOTATION :: L E5 B666 OV MUTJ A1 CQ E1 FV1 L1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 338 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,185,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3713 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 711 (estimated) No. of Female Employees: 328 (estimated)

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6A-甲基-11B-羟孕酮安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TU5250000

6A-甲基-11B-羟孕酮合成路线

详细合成路线

6A-甲基-11B-羟孕酮上下游产品

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6A-甲基-11B-羟孕酮文献

Ocular pemphigus.

J. Egypt. Med. Assoc. 61(7-8) , 511-22, (1978)

Efficacy of medrysone as anti-inflammatory agent.

Indian J. Ophthalmol. 33(5) , 295-7, (1985)

Management of vernal conjunctivitis with steroid induced glaucoma--a comparative study.

Indian J. Ophthalmol. 35(5-6) , 298-301, (1987)

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