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奥芬氨酯

奥芬氨酯用途

Oxyfenamate 是一种抗焦虑药。

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奥芬氨酯名称

[ CAS 号 ]:
50-19-1

[ 中文名 ]:
奥芬氨酯

[ 英文名 ]:
Oxyfenamate

[英文别名 ]:

2-Hydroxy-2-phenylbutyl-carbamat
Phenylbutamate
Hydroxyphenamate
Listica
Oxifenamatum
oxyfenamate
Hidroxifenamato
Tensifen
AL-0361
Oxyphenamate

奥芬氨酯生物活性

[ 描述 ]:

Oxyfenamate 是一种抗焦虑药。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[相关活性小分子]

奥芬氨酯物理化学性质

[ 密度 ]:
1.18g/cm3

[ 沸点 ]:
415.4ºC at 760 mmHg

[ 分子式 ]:
C₁₁H₁₅NO₃

[ 分子量 ]:
209.24200

[ 闪点 ]:
205.1ºC

[ 精确质量 ]:
209.10500

[ PSA ]:
72.55000

[ LogP ]:
2.07980

[ 折射率 ]:
1.545

[ 储存条件 ]:
2-8℃

奥芬氨酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EK2450000

CHEMICAL NAME :: 1,2-Butanediol, 2-phenyl-, 1-carbamate

CAS REGISTRY NUMBER :: 50-19-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C11-H15-N-O3

MOLECULAR WEIGHT :: 209.27

WISWESSER LINE NOTATION :: ZVO1XQ2&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 607 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,394,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 830 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 425 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 233 gm/kg/52W-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Related to Chronic Data - death

REFERENCE :: DNSSAW Diseases of the Nervous System, Supplement. (Irvington, NJ) For publisher information, see DNSYAG. Volume(issue)/page/year: 22,9,1961

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奥芬氨酯安全信息

[ 海关编码 ]:
2924299090

奥芬氨酯海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%