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N-烟酰甘氨酸

N-烟酰甘氨酸用途

Nicotinuric acid是酰基甘氨酸。它是烟酸的代谢产物。

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N-烟酰甘氨酸名称

[ CAS 号 ]:
583-08-4

[ 中文名 ]:
烟酰甘氨酸

[ 英文名 ]:
N-nicotinoyl-Glycine

[中文别名 ]:

[英文别名 ]:

Nicotinursaeure
N-Nicotinylglycine
Glycine, N-(3-pyridinylcarbonyl)-
N-(Pyridin-3-ylcarbonyl)glycine
Nicotinuric acid
N-(3-Pyridinylcarbonyl)glycine
Nicotinylglycine
Nicotinurate
[(3-pyridinylcarbonyl)amino]acetic acid
nicotinicamido acetic acid

N-烟酰甘氨酸生物活性

[ 描述 ]:

Nicotinuric acid是酰基甘氨酸。它是烟酸的代谢产物。

[ 相关类别 ]:

研究领域 >> 其他

天然产物 >> 酸和醛

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Inamadugu JK, et al. Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. Biomed Chromatogr. 2010 Oct;24(10):1059-74.

[相关活性小分子]

N-烟酰甘氨酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
512.5±30.0 °C at 760 mmHg

[ 熔点 ]:
256-2580C (dec.)

[ 分子式 ]:
C₈H₈N₂O₃

[ 分子量 ]:
180.161

[ 闪点 ]:
263.7±24.6 °C

[ 精确质量 ]:
180.053497

[ PSA ]:
79.29000

[ LogP ]:
-0.55

[ 外观性状 ]:
白色固体

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.572

[ 储存条件 ]:
Store at 0-5°C

N-烟酰甘氨酸MSDS

N-烟酰甘氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933399090

N-烟酰甘氨酸合成路线

N-烟酰甘氨酸上下游产品

N-烟酰甘氨酸上游产品

N-烟酰甘氨酸下游产品

N-烟酰甘氨酸海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-烟酰甘氨酸文献

Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine.

Kidney Int. 79(11) , 1244-53, (2011)

Autosomal dominant polycystic kidney disease (ADPKD) is a frequent cause of kidney failure; however, urinary biomarkers for the disease are lacking. In a step towards identifying such markers, we used...

Effects of excess nicotinamide administration on the urinary excretion of nicotinamide N-oxide and nicotinuric acid by rats.

Biosci. Biotechnol. Biochem. 68(1) , 44-50, (2004)

We investigated a useful chemical index for an excessive nicotinamide intake and how this excessive nicotinamide intake affects the tryptophan-nicotinamide metabolism in rats. Weaning rats were fed on...

Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.

Int. J. Clin. Pharmacol. Ther. 45(8) , 448-54, (2007)

To characterize plasma and urine pharmacokinetics of niacin and its metabolites after oral administration of 2,000 mg of extended-release (ER) niacin in healthy male volunteers.Niacin ER was administe...

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