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1,2-二棕榈酰-sn-甘油-3-磷酰胆碱

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱用途

DPPC 是一种磷酸甘油酯,可用于制备脂质体单层。

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1,2-二棕榈酰-sn-甘油-3-磷酰胆碱名称

[ CAS 号 ]:
63-89-8

[ 中文名 ]:
二棕榈酸磷脂酰胆碱

[ 英文名 ]:
Colfosceril palmitate

[中文别名 ]:

[英文别名 ]:

1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine
1,2-Dipalmitoyl-L-3-phosphatidylcholine
Colfosceril palmitate
L-α-DPPC
1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
1,2-Dipalmitoyl-sn-3-glycerophosphocholine
b,g-Dipalmitoyl L-α-phosphatidylcholine
MFCD00036903
1,2-Dipalmitoyl-3-sn-phosphatidylcholine
1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱生物活性

[ 描述 ]:

DPPC 是一种磷酸甘油酯,可用于制备脂质体单层。

[ 相关类别 ]:

天然产物 >> 其他

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.

[相关活性小分子]

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱物理化学性质

[ 熔点 ]:
229-229.5 °C

[ 分子式 ]:
C₄₀H₈₀NO₈P

[ 分子量 ]:
734.039

[ 精确质量 ]:
733.562134

[ PSA ]:
121.00000

[ LogP ]:
10.88

[ 外观性状 ]:
白色结晶粉末

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱MSDS

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱安全信息

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱合成路线

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱上下游产品

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱上游产品

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱下游产品

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱制备

合成表面活性剂，由棕榈胆磷加十六烷基醇和泰洛沙泊(Tyloxapol)组成。

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1,2-二棕榈酰-sn-甘油-3-磷酰胆碱文献

Cardiolipin-incorporated liposomes with surface CRM197 for enhancing neuronal survival against neurotoxicity.

Int. J. Pharm. 473(1-2) , 334-44, (2014)

CRM197-grafted liposomes containing cardiolipin (CL) (CRM197/CL-liposomes) were used to enhance the permeability of neuron growth factor (NGF) across the blood-brain barrier (BBB) for promoting the ne...

HMDB: a knowledgebase for the human metabolome.

Nucleic Acids Res. 37(Database issue) , D603-10, (2009)

The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m...

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