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N-ω-乙酰基组胺

N-ω-乙酰基组胺用途

N-acetylhistamine 是一种组胺代谢物。N-acetylhistamine 可用作过敏反应中组氨酸代谢的生物标志物。

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N-ω-乙酰基组胺名称

[ CAS 号 ]:
673-49-4

[ 中文名 ]:
Nω-乙酰基组胺

[ 英文名 ]:
N-ω-Acetylhistamine

[中文别名 ]:

N-ω-乙酰基组胺

[英文别名 ]:

EINECS 211-610-3
Nomega-Acetylhistamine
N'-Acetylhistamine
N-[2-(1H-imidazol-5-yl)ethyl]acetamide
N-[2-(1H-Imidazol-4-yl)ethyl]acetamide
MFCD00005209
4-(2-acetamidoethyl)imidazole
Nw-acetyl-histamine
Acetylhistamine
N-ω-Acetylhistamine

N-ω-乙酰基组胺生物活性

[ 描述 ]:

N-acetylhistamine 是一种组胺代谢物。N-acetylhistamine 可用作过敏反应中组氨酸代谢的生物标志物。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 组胺受体

信号通路 >> 免疫及炎症 >> 组胺受体

研究领域 >> 炎症/免疫

[体外研究]

N-乙酰组胺是过敏反应的重要指标[1]。

[参考文献]

[1]. Xu Y, et al. Metabolomics analysis of anaphylactoid reaction reveals its mechanism in a rat model. Asian Pac J Allergy Immunol. 2017 Dec;35(4):224-232.

[相关活性小分子]

N-ω-乙酰基组胺物理化学性质

[ 密度 ]:
1.153g/cm3

[ 沸点 ]:
501.7ºC at 760 mmHg

[ 熔点 ]:
147-149ºC(lit.)

[ 分子式 ]:
C₇H₁₁N₃O

[ 分子量 ]:
153.18200

[ 闪点 ]:
257.2ºC

[ 精确质量 ]:
153.09000

[ PSA ]:
57.78000

[ LogP ]:
0.47920

[ 折射率 ]:
1.533

[ 储存条件 ]:
2-8℃

N-ω-乙酰基组胺MSDS

N-ω-乙酰基组胺安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933290090

N-ω-乙酰基组胺合成路线

N-ω-乙酰基组胺上下游产品

N-ω-乙酰基组胺上游产品

N-ω-乙酰基组胺下游产品

N-ω-乙酰基组胺海关

[ 海关编码 ]: 2933290090

[ 中文概述 ]:
2933290090. 其他结构含非稠合咪唑环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

N-ω-乙酰基组胺文献

[Oscillographic polarography of the alkaloid dolicotheline and several related imidazole derivatives].

Farmakol. Toksikol. 44(2) , 220-4, (1981)

Oscillographic polarography in an alkaline medium has shown that the alkaloid N-isovalerylhistamine appears as an expressive wave of the adsorption character in the cathode portion of the curve. This ...

Monooxygenation of N-acetylhistamine mediated by L-ascorbate.

Biochim. Biophys. Acta 991(2) , 377-9, (1989)

In the presence of molecular oxygen and a catalytic amount of copper(II) ion, ascorbate almost completely degraded histamine (approx. 72%). The reaction was shown to occur at the imidazole group but n...

Effects of intracerebroventricular administration of N-acetylhistamine on body temperature in mice.

Methods Find. Exp. Clin. Pharmacol. 16(8) , 575-81, (1994)

The purpose of this study was to examine the effects of intracerebroventricular (i.c.v.) administration of N-acetylhistamine on rectal temperature, histamine level, histidine decarboxylase (HDC) activ...

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