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5,5＇二硫代双(2-硝基苯甲酸)(DTNB)

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)用途

DTNB能对硫醇基进行定量测定,能用于测定纯溶液和生物样品中的低分子量硫醇(如谷胱甘肽)。

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5,5＇二硫代双(2-硝基苯甲酸)(DTNB)名称

[ CAS 号 ]:
69-78-3

[ 中文名 ]:
5,5'-二硫双(2-硝基苯甲酸)

[ 英文名 ]:
DTNB

[中文别名 ]:

[英文别名 ]:

3-Carboxy-4-nitrophenyl disulfide
EINECS 200-714-4
3,3'-Disulfanediylbis(6-nitrobenzoic acid)
Benzoic acid, 3,3'-dithiobis[6-nitro-
Ellman Reagent
MFCD00007140
5,5'-dithiobis-(2-nitrobenzoic acid)
5,5'-DITHIOBIS(2-NITROBENZOIC ACID)
5,5'-Dithobis(2-Nitrobenzoic Acid)
5,5-Dithiobis(2-nitrobenzoic acid)

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)生物活性

[ 描述 ]:

DTNB能对硫醇基进行定量测定,能用于测定纯溶液和生物样品中的低分子量硫醇(如谷胱甘肽)。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

生化试剂

研究领域 >> 其他

[相关活性小分子]

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)物理化学性质

[ 密度 ]:
1.8±0.1 g/cm3

[ 沸点 ]:
671.9±55.0 °C at 760 mmHg

[ 熔点 ]:
240-245 °C (dec.)(lit.)

[ 分子式 ]:
C₁₄H₈N₂O₈S₂

[ 分子量 ]:
396.352

[ 闪点 ]:
360.1±31.5 °C

[ 精确质量 ]:
395.972198

[ PSA ]:
216.84000

[ LogP ]:
3.97

[ 外观性状 ]:
黄色固体

[ 蒸汽压 ]:
0.0±2.2 mmHg at 25°C

[ 折射率 ]:
1.769

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong bases, strong oxidizing agents.

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)MSDS

详细MSDS(安全技术说明书)

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG9650000

CHEMICAL NAME :: Benzoic acid, 3,3'-dithiobis(6-nitro-

CAS REGISTRY NUMBER :: 69-78-3

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H8-N2-O8-S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2080 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,284,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7018 No. of Facilities: 23 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 197 (estimated) No. of Female Employees: 145 (estimated)

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5,5＇二硫代双(2-硝基苯甲酸)(DTNB)安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
DG9650000

[ 海关编码 ]:
29309070

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)上下游产品

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)上游产品

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)下游产品

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

5,5＇二硫代双(2-硝基苯甲酸)(DTNB)文献

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The potent cytotoxicity of reactive oxygen species (ROS) can cause various diseases but may also serve as a powerful weapon capable of destroying cancer cells. Although the balance between generation ...

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