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十二烷二酸

十二烷二酸用途

Dodecanedioic acid (C12) 是二羧酸,是水溶性物质,其代谢途径介于脂质和碳水化合物的中间。

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十二烷二酸名称

[ CAS 号 ]:
693-23-2

[ 中文名 ]:
十二烷二酸

[ 英文名 ]:
Dodecanedioic acid

[中文别名 ]:

[英文别名 ]:

DDA
DDDA
MFCD00002735
n-Dodecanedioic acid
dodecane-1,12-dioic acid
Dodecanedioic acid
UNII-978YU42Q6I
EINECS 211-746-3
DODECANEDIOIC
n-Dodecanedioate

十二烷二酸生物活性

[ 描述 ]:

Dodecanedioic acid (C12) 是二羧酸,是水溶性物质,其代谢途径介于脂质和碳水化合物的中间。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Greco AV, et al. The metabolic effect of dodecanedioic acid infusion in non-insulin-dependent diabetic patients. Nutrition. 1998 Apr;14(4):351-7.

[相关活性小分子]

十二烷二酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
394.0±0.0 °C at 760 mmHg

[ 熔点 ]:
127-129 °C(lit.)

[ 分子式 ]:
C₁₂H₂₂O₄

[ 分子量 ]:
230.301

[ 闪点 ]:
216.6±17.7 °C

[ 精确质量 ]:
230.151810

[ PSA ]:
74.60000

[ LogP ]:
2.92

[ 外观性状 ]:
白色片状

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.475

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, reducing agents. Combustible.

[ 水溶解性 ]:
< 0.1 g/L (20 ºC)

十二烷二酸MSDS

十二烷二酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
-

[ 海关编码 ]:
2917190090

十二烷二酸合成路线

十二烷二酸上下游产品

十二烷二酸上游产品

十二烷二酸下游产品

十二烷二酸制备

工业上可将丁二烯三聚得环十二碳三烯，再经加氢制成环十二烷，再用硝酸氧化经过环十二烷酮而得十二双酸。也可由环已烷为原料，在甲醇中与过氧化氢反应，制成烷氧基环已基过氧化物，再开环、二聚，生成十二双酸甲酯。再经皂化，即可制得十二双酸。实验室制备时，以环十二烷醇为原料，经硝酸氧化可得十二双酸。

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十二烷二酸海关

[ 海关编码 ]: 2917190090

[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

十二烷二酸文献

Chirality of Single-Handed Twisted Titania Tubular Nanoribbons Prepared Through Sol-gel Transcription.

Chirality 27 , 543-50, (2015)

Single-handed twisted titania tubular nanoribbons were prepared through sol-gel transcription using a pair of enantiomers. Handedness was controlled by that of the template. The obtained samples were ...

Use of high-resolution proton nuclear magnetic resonance spectroscopy for rapid multi-component analysis of urine.

Clin. Chem. 30(3) , 426-32, (1984)

Numerous low-Mr metabolites--including creatinine, citrate, hippurate, glucose, ketone bodies, and various amino acids--have been identified in 400- and 500-MHz proton nuclear magnetic resonance (1H N...

1,5-anhydroglucitol and postprandial hyperglycemia as measured by continuous glucose monitoring system in moderately controlled patients with diabetes.

Diabetes Care 29(6) , 1214-9, (2006)

Postprandial hyperglycemia is often inadequately assessed in diabetes management. Serum 1,5-anhydroglucitol (1,5-AG) drops as serum glucose rises above the renal threshold for glucose and has been pro...

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