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7-氨基放线菌素D

7-氨基放线菌素D用途

7-Aminoactinomycin D 是一种荧光 DNA 染色剂。

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7-氨基放线菌素D名称

[ CAS 号 ]:
7240-37-1

[ 中文名 ]:
7-氨基放线菌素D

[ 英文名 ]:
7-Aminoactinomycin D

[英文别名 ]:

7-Aminodactinomycin
MFCD00077295
7AAD
7-Actinomycin C1
7-amino-actinomycin-D
7-amino-AMD
Actinomycin D,7-amino

7-氨基放线菌素D生物活性

[ 描述 ]:

7-Aminoactinomycin D 是一种荧光 DNA 染色剂。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

染料试剂

研究领域 >> 其他

[参考文献]

[1]. Wadkins RM, et al. Actinomycin D and 7-aminoactinomycin D binding to single-stranded DNA. Biochemistry. 1991 Oct 1;30(39):9469-78.

[相关活性小分子]

7-氨基放线菌素D物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
1400.8±65.0 °C at 760 mmHg

[ 分子式 ]:
C₆₂H₈₇N₁₃O₁₆

[ 分子量 ]:
1270.432

[ 闪点 ]:
801.0±34.3 °C

[ 精确质量 ]:
1269.639404

[ PSA ]:
386.00000

[ LogP ]:
-5.02

[ 外观性状 ]:
红色至暗紫色粉末

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.664

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
chloroform: 1 mg/mL, clear, red

7-氨基放线菌素D毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU1579000

CHEMICAL NAME :: Actinomycin D, 7-amino-

CAS REGISTRY NUMBER :: 7240-37-1

LAST UPDATED :: 199409

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C62-H87-N13-O16

MOLECULAR WEIGHT :: 1270.62

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 3 umol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,448,1983

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7-氨基放线菌素D安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300

[ 警示性声明 ]:
Missing Phrase - N15.00950417

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+: Very toxic;

[ 风险声明 (欧洲) ]:
R26/27/28;R36/37/38

[ 安全声明 (欧洲) ]:
26-28-36/37-45

[ 危险品运输编码 ]:
UN 3462 6

[ WGK德国 ]:
3

[ RTECS号 ]:
AU1579000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1(a)

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