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L-异亮氨酸

L-异亮氨酸用途

L-Isoleucine 是二十种蛋白氨基酸中的其中一种。L-Isoleucine 是一种必需氨基酸。

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L-异亮氨酸名称

[ CAS 号 ]:
73-32-5

[ 中文名 ]:
L-异亮氨酸

[ 英文名 ]:
L-Isoleucine

[中文别名 ]:

[英文别名 ]:

Ile
QVYZY2&1 &&(2S,3S)- or L(+)- Form
H-ILE-OH
L-Ile
N-methyl Ile
MFCD00064222
UNII:5HX0BYT4E3
H-DL-Ile-OH
a-Amino-b-methylvaleric Acid
L-Ile (2S,3S)

L-异亮氨酸生物活性

[ 描述 ]:

L-Isoleucine 是二十种蛋白氨基酸中的其中一种。L-Isoleucine 是一种必需氨基酸。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 其他

研究领域 >> 其他

[相关活性小分子]

L-异亮氨酸物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
225.8±23.0 °C at 760 mmHg

[ 熔点 ]:
168-170ºC

[ 分子式 ]:
C₆H₁₃NO₂

[ 分子量 ]:
131.173

[ 闪点 ]:
90.3±22.6 °C

[ 精确质量 ]:
131.094635

[ PSA ]:
63.32000

[ LogP ]:
0.73

[ 外观性状 ]:
无气味的白色固体

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.463

[ 储存条件 ]:
室温

L-异亮氨酸MSDS

L-异亮氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NR4705000

CHEMICAL NAME :: Isoleucine, L-

CAS REGISTRY NUMBER :: 73-32-5

LAST UPDATED :: 199707

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H13-N-O2

MOLECULAR WEIGHT :: 131.20

WISWESSER LINE NOTATION :: QVYZY2&1 -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6822 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4368 mg/kg/13W-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - urine volume increased Nutritional and Gross Metabolic - changes in sodium Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 372,75,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81864 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81864 No. of Facilities: 740 (estimated) No. of Industries: 3 No. of Occupations: 13 No. of Employees: 18202 (estimated) No. of Female Employees: 13865 (estimated)

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L-异亮氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R40

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
NR4705000

[ 海关编码 ]:
29224995

L-异亮氨酸合成路线

L-异亮氨酸上下游产品

L-异亮氨酸上游产品

L-异亮氨酸下游产品

L-异亮氨酸制备

1.以糖、氨、D苏氨酸为原料，经黏质赛式杆菌发酵而得。或以糖、氨、α-氨基丁酸为原料，用黄色小球菌或桔草杆菌发酵后再经精制而得。

2.菌种培养发酵发酵液过滤上层液草酸，H2SO4过滤滤液吸附。

3.洗脱洗脱液浓缩减压蒸馏脱色浓缩减压蒸馏中和氨水沉淀精制结晶。

4.烘干105℃L-异亮氨酸成品。

5.烟草：BU，22；FC，21；合成：可由玉米蛋白等蛋白质水解、精制而得。也可用化学方法合成。

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L-异亮氨酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

L-异亮氨酸文献

A substrate ambiguous enzyme facilitates genome reduction in an intracellular symbiont.

BMC Biol. 12 , 110, (2015)

Genome evolution in intracellular microbial symbionts is characterized by gene loss, generating some of the smallest and most gene-poor genomes known. As a result of gene loss these genomes commonly c...

Use of Commercial Dry Yeast Products Rich in Mannoproteins for White and Rosé Sparkling Wine Elaboration.

J. Agric. Food Chem. 63 , 5670-81, (2015)

In sparkling wines, mannoproteins released during yeast autolysis largely affect their final quality. This process is very slow and may take several months. The aim of this work was to study the effec...

The human serum metabolome.

PLoS ONE 6(2) , e16957, (2011)

Continuing improvements in analytical technology along with an increased interest in performing comprehensive, quantitative metabolic profiling, is leading to increased interest pressures within the m...

更多文献

L-异亮氨酸

L-异亮氨酸用途

L-异亮氨酸名称

L-异亮氨酸生物活性

L-异亮氨酸物理化学性质

L-异亮氨酸MSDS

详细MSDS(安全技术说明书)

L-异亮氨酸毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

L-异亮氨酸安全信息

L-异亮氨酸合成路线

详细合成路线

L-异亮氨酸上下游产品

L-异亮氨酸上游产品

L-异亮氨酸下游产品

L-异亮氨酸制备

L-异亮氨酸海关

L-异亮氨酸文献

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