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茶皂素

茶皂素用途

Saponins 是一类多发现于多种植物中苷类的化合物。Saponins 可保护植物免受微生物和真菌的破坏[1]。

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茶皂素名称

[ CAS 号 ]:
8047-15-2

[ 中文名 ]:
茶皂素

[ 英文名 ]:
Saponins

[中文别名 ]:

[英文别名 ]:

EINECS 232-462-6
SAPONINS
MFCD00081981
SAPONINE
Tea Saponin
Sapogenins glycosides

茶皂素生物活性

[ 描述 ]:

Saponins 是一类多发现于多种植物中苷类的化合物。Saponins 可保护植物免受微生物和真菌的破坏[1]。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

天然产物 >> 糖和糖苷

研究领域 >> 炎症/免疫

[体外研究]

皂苷是具有独特发泡特性的糖苷。皂苷由多环糖苷配基组成,所述多环糖苷配基通过C3连接的胆碱类固醇或三萜类化合物与糖侧链的醚键连接。皂苷发泡的能力是由非极性皂苷元和水溶性侧链的组合引起的。皂苷是苦的并且降低了牲畜饲料的适口性。一些皂苷会降低非反刍动物的采食量和生长速度,而其他一些则不是很有害。例如,在燕麦和菠菜中发现的皂苷会增加并加速身体吸收钙和硅的能力,从而有助于消化。某些牧草杂草含有大量危险的皂甙,对某些动物物种造成危及生命的毒性[1]。

[参考文献]

[1]. "Saponins". Cornell University. 14 August 2008. Retrieved 23 February 2009.

[相关活性小分子]

茶皂素物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 熔点 ]:
158℃

[ 分子式 ]:
C₂₇H₄₂O₃

[ 分子量 ]:
1645.293

[ 精确质量 ]:
1643.942505

[ LogP ]:
28.57

[ 外观性状 ]:
固体

[ 折射率 ]:
1.583

[ 储存条件 ]:
Store at RT.

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
Do you have solubility information on this product that you would like to share | Soluble in cold water.

茶皂素安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37

[ 安全声明 (欧洲) ]:
S26;S37/S39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
VQ1400000

茶皂素制备

以茶籽饼粕为原料，用溶剂提取其中的皂角苷制得。

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茶皂素文献

CAF01 potentiates immune responses and efficacy of an inactivated influenza vaccine in ferrets.

PLoS ONE 6 , e22891, (2011)

Trivalent inactivated vaccines (TIV) against influenza are given to 350 million people every year. Most of these are non-adjuvanted vaccines whose immunogenicity and protective efficacy are considered...

An optimized method to process mouse CNS to simultaneously analyze neural cells and leukocytes by flow cytometry.

J. Neurosci. Methods 247 , 23-31, (2015)

Flow cytometry is an efficient and powerful technique to characterize and quantify numerous cells. However, the strengths of this technique have not been widely harnessed in neurosciences due to the c...

Human dendritic cells infected with an adenoviral vector suppress proliferation of autologous and allogeneic T cells.

Immunology 125(4) , 469-79, (2008)

Dendritic cells (DCs) play a key role in the type and course of an immune response. The manipulation of human DCs to produce therapeutic agents by transduction with viral vectors is a growing area of ...

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茶皂素