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苯芴醇

苯芴醇用途

Lumefantrine是一种抗疟疾药物, 与Artemether联用, 作为一线和二线抗疟药。

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苯芴醇名称

[ CAS 号 ]:
82186-77-4

[ 中文名 ]:
苯芴醇

[ 英文名 ]:
Lumefantrine

[中文别名 ]:

[英文别名 ]:

Benflumetol
Lumefantrine

苯芴醇生物活性

[ 描述 ]:

Lumefantrine是一种抗疟疾药物, 与Artemether联用, 作为一线和二线抗疟药。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[参考文献]

[1]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423.

[相关活性小分子]

苯芴醇物理化学性质

[ 密度 ]:
1.252

[ 沸点 ]:
642.5±55.0 °C at 760 mmHg

[ 熔点 ]:
129-131ºC

[ 分子式 ]:
C₃₀H₃₂Cl₃NO

[ 分子量 ]:
528.940

[ 闪点 ]:
342.3±31.5 °C

[ 精确质量 ]:
527.154968

[ PSA ]:
23.47000

[ LogP ]:
11.37

[ 外观性状 ]:
黄色固体

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.634

[ 储存条件 ]:
Refrigerator

苯芴醇MSDS

详细MSDS(安全技术说明书)

苯芴醇安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2922199090

苯芴醇海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

苯芴醇文献

Antibody and T-cell responses associated with experimental human malaria infection or vaccination show limited relationships.

Immunology 145(1) , 71-81, (2015)

This study examined specific antibody and T-cell responses associated with experimental malaria infection or malaria vaccination, in malaria-naive human volunteers within phase I/IIa vaccine trials, w...

Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity.

Malaria Journal 13 , 359, (2014)

Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolis...

Comparison between Flow Cytometry, Microscopy, and Lactate Dehydrogenase-Based Enzyme-Linked Immunosorbent Assay for Plasmodium falciparum Drug Susceptibility Testing under Field Conditions.

J. Clin. Microbiol. 53 , 3296-303, (2015)

Flow cytometry is an objective method for conducting in vitro antimalarial sensitivity assays with increasing potential for application in field sites. We examined in vitro susceptibility to seven ant...

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苯芴醇

苯芴醇用途

苯芴醇名称

苯芴醇生物活性

苯芴醇物理化学性质

苯芴醇MSDS

详细MSDS(安全技术说明书)

苯芴醇安全信息

苯芴醇海关

苯芴醇文献

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