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氧硫氯酚

氧硫氯酚用途

Bithionol sulfoxide(Bitin-S)是一抗寄生虫化合物,被研究显示具有抗癌活性。

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氧硫氯酚名称

[ CAS 号 ]:
844-26-8

[ 中文名 ]:
氧硫氯酚

[ 英文名 ]:
Bithionol (sulfoxide)

[英文别名 ]:

Sulphene
bithionol sulfoxide
Bithionoloxide
4,6,4',6'-tetrachloro-2,2'-sulfinyl-di-phenol
Disto-5-cogla
Bitionoloxido [Spanish]
Bithionoloxide [INN]
2,2'-sulfinyl-bis(4,6-dichlorophenol)
Bitin S
Distobitin

氧硫氯酚生物活性

[ 描述 ]:

Bithionol sulfoxide(Bitin-S)是一抗寄生虫化合物,被研究显示具有抗癌活性。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 癌症

[参考文献]

[1]. Ayyagari VN, et al. Bithionol inhibits ovarian cancer cell growth in vitro - studies on mechanism(s) of action. BMC Cancer. 2014 Feb 4;14:61.

[2]. Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). Dis Aquat Organ. 2010 Sep 17;91(3):257-62.

[相关活性小分子]

氧硫氯酚物理化学性质

[ 密度 ]:
1.86 g/cm3

[ 沸点 ]:
532.7ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₆Cl₄O₃S

[ 分子量 ]:
372.05100

[ 闪点 ]:
276ºC

[ 精确质量 ]:
369.87900

[ PSA ]:
76.74000

[ LogP ]:
5.74380

[ 外观性状 ]:
灰白色至粉红色结晶粉末

[ 折射率 ]:
1.769

[ 储存条件 ]:
2-8℃

氧硫氯酚MSDS

详细MSDS(安全技术说明书)

氧硫氯酚毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM8800000

CHEMICAL NAME :: Phenol, 2,2'-sulfinylbis(4,6-dichloro-

CAS REGISTRY NUMBER :: 844-26-8

BEILSTEIN REFERENCE NO. :: 2003972

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H6-Cl4-O3-S

MOLECULAR WEIGHT :: 372.04

WISWESSER LINE NOTATION :: QR BG DG FSO&R BQ CG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 188,53,1987

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氧硫氯酚安全信息

[ 海关编码 ]:
2930909090

氧硫氯酚合成路线

详细合成路线

氧硫氯酚上下游产品

氧硫氯酚上游产品

氧硫氯酚下游产品

氧硫氯酚海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%