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N-乙酰-L-天门冬氨酸

N-乙酰-L-天门冬氨酸用途

N-Acetyl-L-aspartic acid 是天冬氨酸的衍生物。

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N-乙酰-L-天门冬氨酸名称

[ CAS 号 ]:
997-55-7

[ 中文名 ]:
N-乙酰基-L-天冬氨酸

[ 英文名 ]:
N-acetyl-L-aspartic acid

[中文别名 ]:

N-乙酰-L-天门冬氨酸

[英文别名 ]:

MFCD00020500
Acide (2S)-2-acétamidosuccinique
Aspartic acid, N-acetyl-, L- (8CI)
N-Acetyl-L-asparticacid
L-N-Acetylaspartic acid
N-Acetyl-L-aspartate
(2S)-2-Acetamidosuccinic acid
L-Aspartic acid, N-acetyl-
Acetylaspartic acid
L-Aspartic acid,N-acetyl

N-乙酰-L-天门冬氨酸生物活性

[ 描述 ]:

N-Acetyl-L-aspartic acid 是天冬氨酸的衍生物。

[ 相关类别 ]:

天然产物 >> 酸和醛

研究领域 >> 其他

[ 靶点 ]

Human Endogenous Metabolite

[参考文献]

[1]. Birken DL, et al. N-acetyl-L-aspartic acid: a literature review of a compound prominent in 1H-NMR spectroscopic studies of brain. Neurosci Biobehav Rev. 1989 Spring;13(1):23-31.

[相关活性小分子]

N-乙酰-L-天门冬氨酸物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
329.1±52.0 °C at 760 mmHg

[ 熔点 ]:
137-140 °C(lit.)

[ 分子式 ]:
C₆H₉NO₅

[ 分子量 ]:
175.139

[ 闪点 ]:
152.8±30.7 °C

[ 精确质量 ]:
175.048065

[ PSA ]:
103.70000

[ LogP ]:
-0.09

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.538

[ 储存条件 ]:
0-10°C;存放于惰性气体之中;避免空气,加热

N-乙酰-L-天门冬氨酸MSDS

N-乙酰-L-天门冬氨酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CI9098600

CHEMICAL NAME :: L-Aspartic acid, N-acetyl-

CAS REGISTRY NUMBER :: 997-55-7

BEILSTEIN REFERENCE NO. :: 1726198

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H9-N-O5

MOLECULAR WEIGHT :: 175.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2660 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,569,1991

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N-乙酰-L-天门冬氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
CI9098600

[ 海关编码 ]:
2924199090

N-乙酰-L-天门冬氨酸合成路线

N-乙酰-L-天门冬氨酸上下游产品

N-乙酰-L-天门冬氨酸上游产品

N-乙酰-L-天门冬氨酸下游产品

N-乙酰-L-天门冬氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N-乙酰-L-天门冬氨酸文献

Age-related reference values for urinary organic acids in a healthy Turkish pediatric population.

Clin. Chem. 40(6) , 862-6, (1994)

Organic acid concentrations were quantified by gas chromatography and the individual acids identified by mass spectrometry in urine specimens from a healthy Turkish pediatric population of ages 2 days...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.

J. Biol. Chem. 282 , 23841-53, (2007)

Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine thei...

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