2-氰基苯甲醛

2-氰基苯甲醛结构式
2-氰基苯甲醛结构式
品牌特惠专场
常用名 2-氰基苯甲醛 英文名 2-Cyanobenzaldehyde
CAS号 7468-67-9 分子量 131.131
密度 1.2±0.1 g/cm3 沸点 284.9±23.0 °C at 760 mmHg
分子式 C8H5NO 熔点 103-105 °C(lit.)
MSDS 中文版 美版 闪点 126.1±22.6 °C
符号 GHS07
GHS07
信号词 Warning

Diastereoselective one-pot tandem synthesis of 3-substituted isoindolinones: a mechanistic investigation.

J. Org. Chem. 75(17) , 5882-7, (2010)

The mechanism of a base-catalyzed one-pot reaction of 2-cyanobenzaldehyde and primary nitroalkanes, to produce 3-substituted isoindolinones, has been investigated. A route starting with a nitroaldol (Henry) reaction, followed by a subsequent cyclization and r...

Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones.

Beilstein J. Org. Chem. 11 , 2591-9, (2015)

New bifunctional chiral ammonium salts were investigated in an asymmetric cascade synthesis of a key building block for a variety of biologically relevant isoindolinones. With this chiral compound in hand, the development of further transformations allowed fo...

The aldol addition of readily enolizable 1, 3-dicarbonyl compounds to 2-cyanobenzaldehyde in the synthesis of novel 3-substituted isoindolinones. More V, et al.

Synthesis 2011(18) , 3027-31, (2011)

Application of baylis-hillman methodology in a new synthesis of 3-oxo-2, 3-dihydro-1H-isoindoles. Song YS, et al.

J. Heterocycl. Chem. 40(5) , 939-42, (2003)

Biotransformation of aromatic aldehydes and related compounds by Euglena gracilis Z. Noma Y, et al.

Phytochemistry 30(9) , 2969-72, (1991)

Novel synthesis of 3-(N-substituted amino)-1-isoindolenones from 2-cyanobenzaldehyde with amines. Sato R, et al.

Chem. Lett. 9 , 1599-1602, (1984)